QUALITY-OF-LIFE IN ADULT SURVIVORS OF LUNG, COLON AND PROSTATE-CANCER
QUALITY-OF-LIFE IN ADULT SURVIVORS OF LUNG, COLON AND PROSTATE-CANCER
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DOI：
10.1007/bf00435256
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发表时间：
1994-04-01
影响因子：
3.5
通讯作者：
LEE, JJ
中科院分区：
文献类型：
--
作者：
SCHAG, CAC;GANZ, PA;LEE, JJ
在一项横断面研究设计中，57名肺癌患者、117名结肠癌患者和104名前列腺癌患者（代表短期、中期和长期幸存者）的无病样本使用癌症康复评估系统（CARES）完成了生活质量（QOL）和康复需求的详细评估。还评估了人口和医疗数据、社会支持和全球生活质量评级。肺癌患者在生存期方面的生活质量没有差异。结肠癌幸存者的生活质量随着寿命的延长而提高，而前列腺癌幸存者的生活质量则随着时间的延长而下降。虽然其他变量如医院类型、性别和工作状态对结肠癌幸存者有预测作用，但所有组的生活质量的最佳预测指标是KPS。对于前列腺癌合并其他内科疾病的幸存者，自诊断以来的时间和因精神困难引起的合并症可预测生活质量。所有群体在身体、社会心理、性、医疗互动和婚姻关系方面都存在显著的康复问题。肺癌幸存者比其他癌症幸存者有更多的问题。我们的结论是，癌症存活下来的病人不会恢复到正常的健康状态。他们表现出各种各样的困难，他们必须应付，因为他们继续生存。需要在早期诊断和治疗方面做出更大的努力，以了解康复问题和有针对性的干预措施，以期减少后期的后遗症。
In a cross-sectional study design, a disease free sample of 57 lung, 117 colon, and 104 prostate cancer survivors who represented short, intermediate and long-term survivors completed a detailed assessment of quality of life (QOL) and rehabilitation needs using the CAncer Rehabilitation Evaluation System (CARES). Demographic and medical data, social support, and a global QOL rating were also assessed. Lung cancer patients showed no differences in QOL with respect to their period of survival. QOL improved for survivors of colon cancer as they lived for longer periods, but declined with time for survivors of prostate cancer. The best predictor of QOL for all groups was KPS, although other variables such as type of hospital, gender, and work status were predictive for survivors of colon cancer. For survivors of prostate cancer comorbidity with other medical illnesses, time since diagnosis and comorbidity due to psychiatric difficulties were predictive of QOL. All groups had significant rehabilitation problems in the domains of physical, psychosocial, sexual, medical interaction, and marital relationships. Lung cancer survivors had more problems than the other cancer survivors. We conclude that patients who survive cancer do not return to a state of normal health. They demonstrate a variety of difficulties with which they must cope as they continue to survive. Greater efforts need to be made early in diagnosis and treatment to understand rehabilitation problems and target interventions in the hope of reducing later sequelae.