SUSTAINED OFF-RESONANCE IRRADIATION FOR COLLISION-ACTIVATED DISSOCIATION INVOLVING FOURIER-TRANSFORM MASS-SPECTROMETRY - COLLISION-ACTIVATED DISSOCIATION TECHNIQUE THAT EMULATES INFRARED MULTIPHOTON DISSOCIATION
SUSTAINED OFF-RESONANCE IRRADIATION FOR COLLISION-ACTIVATED DISSOCIATION INVOLVING FOURIER-TRANSFORM MASS-SPECTROMETRY - COLLISION-ACTIVATED DISSOCIATION TECHNIQUE THAT EMULATES INFRARED MULTIPHOTON DISSOCIATION
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DOI：
10.1016/s0003-2670(00)80678-9
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发表时间：
1991-05-15
影响因子：
6.2
通讯作者：
JACOBSON, DB
中科院分区：
文献类型：
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作者：
GAUTHIER, JW;TRAUTMAN, TR;JACOBSON, DB
描述了一种涉及傅里叶变换质谱 (FTMS) 的碰撞激活解离 (CAD) 方法。 在传统的 FTMS-CAD 中，通过施加短持续时间（< 500-mu-s）的共振电场脉冲来平移激发离子。 随后与中性目标的非弹性碰撞导致碎片。 现在表明，CAD 也可以通过应用持续（大于或等于 500 毫秒）偏共振 (SORI) 电场脉冲来实现。 “共振”和“非共振”照射之间的 CAD 差异涉及离子获得的最大平移能量、激发的时间尺度以及影响解离的碰撞次数。 SORI-CAD 通过低动能离子 (< 10 eV) 与目标的多次碰撞来顺序激活离子。 因此，在电场脉冲的整个持续时间内，只有少量的内部能量被转移到离子。 这种激活模式类似于使用低功率连续波 (CW) CO2 激光器进行的红外多光子解离 (IRMPD)，可对最低能量分解路径进行采样。 同样，SORI-CAD 是离子最低能量分解路径的选择性探针。 描述了许多模型系统的 SORI-CAD，并讨论了这种新 CAD 方法在化学问题中的潜在应用。
A method for collision-activated dissociation (CAD) involving Fourier transform mass spectrometry (FTMS) is described. In conventional FTMS-CAD an ion is translationally excited by applying a short duration (< 500-mu-s) resonant electric field pulse. Subsequent inelastic collisions with a neutral target result in fragmentation. It is now shown that CAD can also be effected by application of a sustained (greater-than-or-equal-to 500 ms) off-resonance (SORI) electric field pulse. The differences for CAD between "on-resonance" and "off-resonance" irradiation involve the maximum translational energy obtained by the ions, the time scale for excitation and the number of collisions effecting dissociation. SORI-CAD results in sequential activation of ions by multiple collisions of low (< 10 eV) kinetic energy ions with the target. As a consequence, only small increments of internal energy are transferred to the ion throughout the duration of the electric field pulse. This mode of activation is analogous to infrared multiphoton dissociation (IRMPD) by using low-power continuous wave (CW) CO2 lasers which allow the lowest energy decomposition pathway to be sampled. SORI-CAD is, likewise, a selective probe of the lowest energy decomposition pathway of ions. SORI-CAD of a number of model systems is described and potential applications of this new CAD method to chemical problems are discussed.