Inhibiting effect of aqueous extracts of eight Nigerian chewing sticks on bacterial properties favouring plaque formation.
Inhibiting effect of aqueous extracts of eight Nigerian chewing sticks on bacterial properties favouring plaque formation.
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八种尼日利亚咀嚼棒的水提取物对有利于牙菌斑形成的细菌特性的抑制作用。
DOI：
10.1159/000260674
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发表时间：
1983
期刊：
影响因子：
4.2
通讯作者：
Sote,EO
中科院分区：
文献类型：
--
作者：
Wolinsky,LE;Sote,EO
尼日利亚咀嚼棒被大量尼日利亚人口用作传统牙刷的替代品。最近已经观察到并记录到，咀嚼这些棒的人中，龋齿和牙周病的发病率降低[Enwonwu，1974]。虽然它们的有益效果的一部分可能是由于机械清洁和去除牙菌斑，但似乎值得考虑咀嚼棒释放的物质可能产生的抑制作用。据推测，这些棒可能含有特异性抑制斑块形成的化疗剂[Newbrun，1978]。尼日利亚研究人员已经部分验证了这一假设，他们表明几种咀嚼棒的缓冲提取物抑制了琼脂平板上口腔细菌的生长[El-said等人，1971年]，然而，这项研究中提出的数据不是很详细，反映了需要更多的实验。因此，本研究的目的是检查八种常用咀嚼棒的水提取物，并确定它们是否表现出一些抗菌或抗牙菌斑特性。使用最近开发的体外试验，我们确定了咀嚼棒提取物对蔗糖介导的生长、乳酸产生和玻璃粘附的影响。
Nigerian chewing sticks are used as an alternative to the conventional toothbrush by a large Nigerian population. It has re cently been observed and documented that there is a decreased incidence of car ies and periodontal disease among per sons who chew these sticks [Enwonwu, 1974], Although part of their beneficial ef fect may be due to mechanical cleansing and removal of plaque, it seemed worth while to consider inhibitory effects which may be exerted by substances released from the chewing sticks. It has been hy pothesized that these sticks might contain chemotherapeutic agents which specifical ly inhibit plaque formation [Newbrun, 1978]. This hypothesis has been partially validated by Nigerian researchers who showed that buffered extracts of several chewing sticks inhibited the growth of oral bacteria on agar plates [El-said et al., 1971], However, the data presented in this study were not very detailed and reflected a need for more experimentation. There fore, the purpose of the present study was to examine aqueous extracts of eight com monly used chewing sticks and determine whether they exhibit some anti-bacterial or anti-plaque properties. Using a recently developed in vitro assay we determined the effect of the chewing stick extracts on the sucrose-mediated, growth, lactic acid production, and adherence to glass of