The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging
The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging
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DOI：
10.1007/s12603-011-0075-8
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发表时间：
2011-12-01
影响因子：
5.8
通讯作者：
Rodriguez-Manas, L.
中科院分区：
文献类型：
--
作者：
Garcia-Garcia, F. J.;Gutierrez Avila, G.;Rodriguez-Manas, L.
评估脆弱综合征的患病率及其相关变量在托莱多省（西班牙）的老年人人群中。数据来自托莱多健康老龄化研究，一项基于人群的研究，对2，488名65岁及以上的人进行。研究参与者是从托莱多市人口普查中通过两阶段随机抽样选出的，涵盖了来自农村和城市的机构和社区居民。数据收集于2006年至2009年，包括社会支持，日常生活活动，合并症，体力活动，生活质量，抑郁症状和认知功能的信息。此外，一名护士收集了人体测量数据，进行了体能测试（步行速度、上肢和下肢力量以及从椅子上站立和坐下测试），并采集了血液样本。虚弱综合征的诊断基于Fried标准（虚弱、速度慢、体力活动少、疲惫和体重减轻），总共有41.8%（95%置信区间[CI] 39.4-44.2%）的研究参与者处于虚弱前期，8.4%（95% CI 7.1-9.8%）的参与者处于虚弱期。在性别、教育水平、职业、婚姻状况或居住地方面，虚弱的患病率没有差异。脆弱综合征的频率随着年龄的增长而增加，并且在残疾、抑郁症、髋部骨折和其他合并症（如心血管疾病和中枢神经系统疾病）的患者中更高。西班牙老年人脆弱综合征的患病率很高，与地中海盆地其他人群的患病率相似。
To assess the prevalence of the frailty syndrome and its associated variables among the older adult population in the province of Toledo (Spain).Data were taken from the Toledo Study for Healthy Aging, a population-based study conducted on 2,488 individuals aged 65 years and older. Study participants were selected by a two-stage random sampling from the municipal census of Toledo, covering both institutionalized and community dwelling persons from rural and urban settings. Data were collected from 2006 to 2009, and included information on social support, activities of daily living, comorbidity, physical activity, quality of life, depressive symptoms, and cognitive function. In addition, a nurse collected anthropometric data, conducted tests of physical performance (walk speed, upper and lower extremities strength, and the stand-and-sit from a chair test) and obtained a blood sample. The diagnosis of the frailty syndrome was based on the Fried criteria (weakness, low speed, low physical activity, exhaustion, and weight loss).In total, 41.8% (95% confidence interval [CI] 39.4-44.2%) of the study participants were prefrail, and 8.4% (95% CI 7.1-9.8%) were frail. There were no differences in the prevalence of frailty by sex, level of education, occupation, marital status, or place of residence. The frequency of the frailty syndrome increased with age, and was higher in those with disability, depression, hip fracture and other comorbidity, such as cardiovascular disease and disorders of the central nervous system.The prevalence of the frailty syndrome in older Spanish adults is high and similar to that reported in other populations in the Mediterranean basin.