Sharp and sleepy: evidence for dissociation between sleep pressure and nocturnal performance
Sharp and sleepy: evidence for dissociation between sleep pressure and nocturnal performance
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DOI：
10.1111/j.1365-2869.2008.00629.x
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发表时间：
2008-03-01
影响因子：
4.4
通讯作者：
Philip, Pierre
中科院分区：
文献类型：
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作者：
Galliaudi, Elodie;Taillard, Jacques;Philip, Pierre
虽然睡眠限制会降低表现，但并非所有人对睡眠不足的敏感性都是一样的。我们测试了这一假设，即性能可以独立于睡眠压力定义的脑电图α-θ功率。20名健康受试者（10名易受影响者和10名抵抗者）接受了25 h的睡眠剥夺。受试者必须评估他们的嗜睡（Karolinska嗜睡量表），并每2小时（20：00 - 08：00）进行一次10分钟的心理警觉任务（PVT）。通过EEG功率谱分析（α-θ频带6.0 - 9.0 Hz）测量睡眠压力。两组的初始性能、EEG谱功率和KSS评分相等（ANOVA，NS）。易受攻击的受试者的表现在夜间显著增加（rANOVA，P < 0.01），而抵抗的受试者总体上保持了他们的表现。在两个类别中（rANOVA，NS），稳态压力和主观嗜睡在夜间显著增加（rANOVA，P < 0.01）。抵抗的受试者保持他们的反应时间独立于稳态压力的增加。易长时间觉醒的表型决定因素仍然未知。
While sleep restriction decreases performance, not all individuals are equal with regard to sensitivity to sleep loss. We tested the hypothesis that performance could be independent of sleep pressure as defined by EEG alpha-theta power. Twenty healthy subjects (10 vulnerable and 10 resistant) underwent sleep deprivation for 25 h. Subjects had to rate their sleepiness (Karolinska Sleepiness Scale) and to perform a 10-min psychomotor vigilance task (PVT) every 2 h (20:00 - 08:00 hours). Sleep pressure was measured by EEG power spectral analysis (alpha-theta band 6.0 - 9.0 Hz). Initial performance, EEG spectral power and KSS score were equal in both groups (ANOVA, NS). The performance of vulnerable subjects significantly increased during the night (rANOVA, P < 0.01), whereas resistant subjects globally sustained their performance. Homeostatic pressure and subjective sleepiness significantly increased during the night (rANOVA, P < 0.01) identically in both categories (rANOVA, NS). Resistant subjects sustained their reaction time independently of the increase in homeostatic pressure. The phenotypic determinants of vulnerability to extended wakefulness remain unknown.