Focusing capillary jets close to the continuum limit
Focusing capillary jets close to the continuum limit
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DOI：
10.1038/nphys710
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发表时间：
2007-10-01
期刊：
影响因子：
19.6
通讯作者：
Flores-Mosquera, Maria
中科院分区：
文献类型：
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作者：
Ganan-Calvo, Alfonso M.;Gonzalez-Prieto, Roman;Flores-Mosquera, Maria
对能够可靠地输送和控制纳米级液体体积的技术的需求是生物技术和医学中日益增长的优先事项。毛细管射流能够提供稳定的单分散液滴流。但是，由于需要越来越大的力和压力来抵消尺寸减小的液滴的表面张力，用这种方法达到纳米级是困难的。克服这种限制的一种方法是当射流从毛细管中出现时静电聚焦射流。另一个，我们在这里报告，是集中这样一个射流的流体动力学手段，一个双流聚焦安排，涉及一个歧管毛细管，提供第二个不混溶的流体射流，信封和引导射流从内部毛细管。在适当的工作条件下，这使得能够产生连续稳定的毛细流体射流，其直径下降到亚微米-接近最终的连续极限，这得到了所提出的理论的支持。
The demand for techniques that can reliably deliver and control nanometre-scale volumes of liquid is a growing priority in biotechnology and medicine. Capillary jets are capable of supplying a steady stream of monodisperse liquid droplets. But because of the increasing forces and pressures needed to counteract surface tension for droplets of decreasing size, reaching the nanoscale with such an approach is difficult. One way of overcoming such limitations is to electrostatically focus a jet as it emerges from a capillary. Another, which we report here, is to focus such a jet by hydrodynamic means, a double flow-focusing arrangement that involves a manifold capillary that delivers a second immiscible fluid jet that envelopes and guides the jet from an inner capillary. Under the appropriate working conditions, this enables the generation of continuous steady capillary fluid jets down to submicrometre diameter - approaching the ultimate continuum limit, which is supported by a proposed theory.