Differentiation of the various lesions causing an abnormality of the endometrial cavity using MR imaging: emphasis on enhancement patterns on dynamic studies and late contrast-enhanced T1-weighted images
Differentiation of the various lesions causing an abnormality of the endometrial cavity using MR imaging: emphasis on enhancement patterns on dynamic studies and late contrast-enhanced T1-weighted images
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DOI：
10.1007/s00330-005-0085-1
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发表时间：
2006-07-01
影响因子：
5.9
通讯作者：
Ahn, Geung Hwan
中科院分区：
文献类型：
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作者：
Park, Byung Kwan;Kim, Bohyun;Ahn, Geung Hwan
本研究的目的是确定磁共振成像（MR）的有效性，通过评价动态增强研究和后期对比增强T1加权像（T1 WI）的成像特征，在各种病变引起的异常子宫内膜腔的鉴别诊断。对比增强MR成像的59个病理证实的病变，显示异常的子宫内膜腔，包括32个子宫内膜癌，5肉瘤，9增生性息肉，9粘膜下肌瘤，3增生，和一个腺肌瘤，进行了回顾性分析。比较不同病变在动态增强扫描和T1 WI延迟增强扫描上的强化程度和强化方式。在动态增强研究中，72%（23/32）的子宫内膜癌在静脉注射造影剂后1分钟内出现早期峰值增强。T1 WI增强扫描病灶呈弱强化，逐渐消退。95%（21/22）的良性病变和100%（5/5）的肉瘤在静脉注射造影剂后2-3分钟内出现晚期峰值强化。在T1 WI上，这两个病灶都表现为持续的强强化。动态增强MRI和延迟增强T1 WI上不同的增强模式可以为鉴别引起子宫内膜腔异常的各种病变提供有用的线索。
The objectives of this study were to determine the usefulness of magnetic resonance (MR) imaging in the differentiation of various lesions causing an abnormality of the endometrial cavity by evaluating the imaging features on dynamic contrast-enhanced study and late contrast-enhanced T1-weighted images (T1WI). Contrast-enhanced MR imaging of 59 pathologically proven lesions that showed an abnormality of the endometrial cavity, including 32 endometrial cancers, five sarcomas, nine hyperplastic polyps, nine submucosal myomas, three hyperplasia, and one adenomyoma, were retrospectively reviewed. The enhancement degree and patterns on dynamic contrast-enhanced study and late contrast-enhanced T1WI were compared among different pathologies. On dynamic contrast-enhanced study, 72% (23/32) of endometrial cancers showed early peak enhancement to be reached within 1 min following intravenous administration of contrast material. On late-contrast-enhanced T1WI, lesions showed weak enhancement with gradual washout. Ninety-five percent (21/22) of benign lesions and 100% (5/5) of sarcomas showed late peak enhancement to be reached in 2-3 min following intravenous administration of contrast material. On late contrast-enhanced T1WI, both of these lesions showed persistent strong enhancement. Different enhancement patterns on dynamic contrast-enhanced MR imaging and late contrast-enhanced T1WI can provide a useful clue in the differentiation of various lesions causing an abnormality of the endometrial cavity.