Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro

Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro
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DOI:
10.1271/bbb.65.1645
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发表时间:
2001-07-01
影响因子:
1.6
通讯作者:
Niwa, A
Niwa, A
中科院分区:
工程技术4区
文献类型:
--
作者:
Sorimachi, K;Ikehara, Y;Niwa, A

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研究了巴西蘑菇的抗病毒活性。用不同浓度的乙醇对培养菌丝体和子实体的水提液进行分级。对几种对VERO细胞具有致细胞病变效应(CPE)的病毒,测试了乙醇组分对这些效应的抑制作用。在菌丝体组分中观察到对西部马脑炎(WEE)病毒诱导的CPE的强烈抑制,但子实体中没有。
Anti-viral activities of Agaricus blazei Murill were investigated. The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol. To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethanol fractions was tested. Strong inhibition of CPE induced by western equine encephalitis (WEE) virus was observed in the mycelial fractions but not those of fruiting bodies.