Physical validation of UF-RIPSA: A rapid in-clinic peak skin dose mapping algorithm for fluoroscopically guided interventions.

Physical validation of UF-RIPSA: A rapid in-clinic peak skin dose mapping algorithm for fluoroscopically guided interventions.
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DOI:
10.1002/acm2.12312
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发表时间:
2018-05
影响因子:
2.1
通讯作者:
Bolch WE
Bolch WE
中科院分区:
医学4区
文献类型:
--
作者:
Borrego D;Marshall EL;Tran T;Siragusa DA;Bolch WE

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本研究的目的是通过实验验证 UF-RIPSA,这是佛罗里达大学使用光刺激发光剂量计 (OSLD) 和组织等效体模开发的一种快速临床峰值皮肤剂量映射算法。本研究中使用的 OSLD 是 Landauer, Inc. 的 InLightTM 纳米点剂量计。OSLD 在自由空气中或在组织等效模型表面上时暴露于九种不同的光束质量。然后使用蒙特卡罗技术对 OSLD 的辐照进行建模,以得出自由空气暴露和更复杂的辐照几何形状之间的校正因子。使用由西门子 Artis zee 双平面荧光镜装置产生的两个荧光镜 X 射线场照射组织等效体模表面上的 OSLD 网格。记录网格内每个 OSLD 的位置,并将其剂量读数与 UF-RIPSA 结果进行比较。通过使用蒙特卡罗校正因子,可以根据 OSLD 的自由空气响应来预测复杂辐照几何形状下的 OSLD 响应。预测值的百分比误差为 -8.7% 至 +3.2%,预测值平均比测量值低 5%。当直接照射在体模上时,观察到 OSLD 和 RIPSA 值之间的一致性在 9% 以内,而当光束首先穿过桌面和垫子时,OSLD 和 RIPSA 值之间的一致性在 14% 以内。 UF-RIPSA 仅计算直接位于 X 射线场内的受照射皮肤区域的剂量值,因为该算法基于报告的参考空气比释动值的射线追踪,并随后对空气到组织剂量转换、X 射线反向散射和工作台/垫衰减进行校正。因此,UF-RIPSA 算法不包括相邻场散射辐射的剂量贡献。尽管存在这一限制,但在计算接受荧光镜引导干预的患者皮肤剂量时,UF-RIPSA 表现出相当稳健的性能。
The purpose of this study was to experimentally validate UF‐RIPSA, a rapid in‐clinic peak skin dose mapping algorithm developed at the University of Florida using optically stimulated luminescent dosimeters (OSLDs) and tissue‐equivalent phantoms. The OSLDs used in this study were InLightTM Nanodot dosimeters by Landauer, Inc. The OSLDs were exposed to nine different beam qualities while either free‐in‐air or on the surface of a tissue equivalent phantom. The irradiation of the OSLDs was then modeled using Monte Carlo techniques to derive correction factors between free‐in‐air exposures and more complex irradiation geometries. A grid of OSLDs on the surface of a tissue equivalent phantom was irradiated with two fluoroscopic x ray fields generated by the Siemens Artis zee bi‐plane fluoroscopic unit. The location of each OSLD within the grid was noted and its dose reading compared with UF‐RIPSA results. With the use of Monte Carlo correction factors, the OSLD's response under complex irradiation geometries can be predicted from its free‐in‐air response. The predicted values had a percent error of −8.7% to +3.2% with a predicted value that was on average 5% below the measured value. Agreement within 9% was observed between the values of the OSLDs and RIPSA when irradiated directly on the phantom and within 14% when the beam first traverses the tabletop and pad. The UF‐RIPSA only computes dose values to areas of irradiated skin determined to be directly within the x ray field since the algorithm is based upon ray tracing of the reported reference air kerma value, with subsequent corrections for air‐to‐tissue dose conversion, x ray backscatter, and table/pad attenuation. The UF‐RIPSA algorithm thus does not include the dose contribution of scatter radiation from adjacent fields. Despite this limitation, UF‐RIPSA is shown to be fairly robust when computing skin dose to patients undergoing fluoroscopically guided interventions.
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