Tear Meniscus Imaging by Anterior Segment-Optical Coherence Tomography in Medically Controlled Glaucoma
Tear Meniscus Imaging by Anterior Segment-Optical Coherence Tomography in Medically Controlled Glaucoma
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DOI：
10.1097/ijg.0000000000001469
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发表时间：
2020-05-01
影响因子：
2
通讯作者：
Mastropasqua, Leonardo
中科院分区：
文献类型：
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作者：
Agnifili, Luca;Brescia, Lorenza;Mastropasqua, Leonardo
目的：摘要本研究的目的是利用前段光学相干断层扫描（AS-OCT）来探讨药物控制青光眼患者（MCGP）的泪膜。材料和方法：选择五十六例MCGP，其中蒸发性干眼（EDE）患者24例，健康对照组30例。MCGP分为β受体阻滞剂组（14只眼）、前列腺素类似物组（14只眼）和≥ 2种药物组（28只眼）。进行眼表疾病指数（OSDI）问卷调查、泪膜破裂时间、角膜荧光素染色、Schirmer试验I和使用AS-OCT的泪半月板高度（下和上：L-TMH、U-TMH）和面积（L-TMA、U-TMA）。结果：OSDI评分高于对照组（P
Purpose: The purpose of this study was to investigate the tear meniscus in medically controlled glaucoma patients (MCGP) using anterior segment-optical coherence tomography (AS-OCT). Materials and Methods: Fifty-six MCGP, 24 patients with evaporative dry eye (EDE), and 30 healthy subjects (controls), were enrolled. MCGP were divided into group 1 (14 eyes): beta-blockers; group 2 (14 eyes): prostaglandin analogs; group 3 (28 eyes) >= 2 drugs. Ocular Surface Disease Index (OSDI) questionnaire, tear film break-up time, corneal fluorescein staining, Schirmer Test I, and tear meniscus height (lower and upper: L-TMH, U-TMH) and area (L-TMA, U-TMA) using AS-OCT, were performed. Results: OSDI score was higher (P