Resazurin microtiter assay plate:: Simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis
Resazurin microtiter assay plate:: Simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis
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DOI：
10.1128/aac.46.8.2720-2722.2002
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发表时间：
2002-08-01
影响因子：
4.9
通讯作者：
Portaels, F
中科院分区：
文献类型：
--
作者：
Palomino, JC;Martin, A;Portaels, F
描述了一种通过还原刃天青检测多药耐药结核分枝杆菌的方法。80个临床分离株进行了评价，对异烟肼和利福平，在7天的结果进行了比较的比例法。特异性和灵敏度均良好。该方法简便、价廉、快速，可与其他抗结核药物联用。
A method for detecting multidrug-resistant Mycobacterium tuberculosis by using a reduction of resazurin is described. Eighty clinical isolates were evaluated against isoniazid and rifampin; results at 7 days were compared with those of the proportion method. Specificity and sensitivity were excellent. The method is simple, inexpensive, and rapid and might be used with other antituberculosis drugs.