Volume Loss and Recovery in Bovine Knee Meniscus Loaded in Circumferential Tension.
Volume Loss and Recovery in Bovine Knee Meniscus Loaded in Circumferential Tension.
复制标题
承受圆周张力的牛膝关节半月板的体积损失和恢复。
DOI：
10.1115/1.4062142
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Elliott,DawnM
中科院分区：
文献类型：
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作者：
Peloquin,JohnM;Santare,MichaelH;Elliott,DawnM
负荷引起的体积变化是膝关节半月板功能的一个重要方面，因为体积损失会产生流体压力，从而最大限度地减少摩擦并有助于支撑压缩负荷。膝关节半月板在软骨组织中是不寻常的，因为它不仅承受轴向压缩，而且承受胫骨附件之间的周向张力。尽管膝关节半月板的拉伸特性具有生理重要性，但其拉伸体积应变从未被直接测量，并且科学文献中的体积应变预测不一致。在这项研究中，我们施加单轴拉伸牛膝关节半月板，并使用双平面成像直接观察所产生的三维体积变化和卸载恢复，揭示了张力导致体积收缩。已知压缩也会引起收缩;因此，所有主要生理负荷都会压缩半月板并使其加压，从而引起液体流出。虽然被动卸载恢复通常被描述为相对于加载损失缓慢，在这里，我们表明，在生理应变的体积恢复率在半月板卸载后是快于体积损失的速度。这些体积应变的测量是迈向膝关节半月板流体流动和负荷支持的完整理论的重要一步。
Load-induced volume change is an important aspect of knee meniscus function because volume loss creates fluid pressure, which minimizes friction and helps support compressive loads. The knee meniscus is unusual amongst cartilaginous tissues in that it is loaded not only in axial compression, but also in circumferential tension between its tibial attachments. Despite the physiologic importance of the knee meniscus' tensile properties, its volumetric strain in tension has never been directly measured, and predictions of volume strain in the scientific literature are inconsistent. In this study, we apply uniaxial tension to bovine knee meniscus and use biplanar imaging to directly observe the resulting three-dimensional volume change and unloaded recovery, revealing that tension causes volumetric contraction. Compression is already known to also cause contraction; therefore, all major physiologic loads compress and pressurize the meniscus, inducing fluid outflow. Although passive unloaded recovery is often described as slow relative to loaded loss, here we show that at physiologic strains the volume recovery rate in the meniscus upon unloading is faster than the rate of volume loss. These measurements of volumetric strain are an important step toward a complete theory of knee meniscus fluid flow and load support.