Meniere's disease
Meniere's disease
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DOI：
10.1016/s0140-6736(08)61161-7
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发表时间：
2008-08-02
期刊：
影响因子：
168.9
通讯作者：
Paparella, Michael M.
中科院分区：
文献类型：
--
作者：
Sajjadi, Hamed;Paparella, Michael M.
梅尼埃病是一种慢性疾病，每年影响全世界大量患者。该疾病的特点是间歇性眩晕发作，持续数分钟至数小时，伴有波动性感音神经性听力损失、耳鸣和耳压。尽管目前尚无治愈方法，但超过 85% 的梅尼埃病患者可以通过改变生活方式和药物治疗，或微创外科手术（如鼓室内类固醇治疗、鼓室内庆大霉素治疗和内淋巴囊手术）得到帮助。前庭神经切除术的眩晕控制率非常高，适用于所有其他治疗均失败的听力良好的患者。迷路切除术是最后的手段，最好保留给患有单侧疾病和耳聋的患者。
Meniere's disease is a chronic illness that affects a substantial number of patients every year worldwide. The disease is characterised by intermittent episodes of vertigo lasting from minutes to hours, with fluctuating sensorineural hearing loss, tinnitus, and aural pressure. Although there is currently no cure, more than 85% of patients with Meniere's disease are helped by either changes in lifestyle and medical treatment, or minimally invasive surgical procedures such as intratympanic steroid therapy, intratympanic gentamicin therapy, and endolymphatic sac surgery. Vestibular neurectomy has a very high rate of vertigo control and is available for patients with good hearing who have failed all other treatments. Labyrinthectomy is undertaken as a last resort and is best reserved for patients with unilateral disease and deafness.