HIV and depression: 2008 review and update.
HIV and depression: 2008 review and update.
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DOI：
10.1007/s11904-008-0025-1
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发表时间：
2008-11-01
影响因子：
4.6
通讯作者：
Rabkin, Judith G
中科院分区：
文献类型：
--
作者：
Rabkin, Judith G
自从艾滋病流行的早期，临床医生就一直关注患者中抑郁症的流行。流行病学家、精神病学家、心理学家、社会学家和其他广泛的专家都研究过这个话题，试图确定抑郁症和抑郁症状的患病率以及前因、相关因素和后果。这篇综述讨论了确定抑郁症患病率的方法学困难，关于疾病发生率的主要发现以及HIV社区不同部分之间的相关性，抑郁症对HIV疾病进展的影响，精神药理学和精神治疗学治疗结果，以及抑郁症的行为影响，如其对药物依从性，就业和风险行为的影响。最后，文章总结了发展中国家抑郁症患病率的国际研究，以及跨国诊断定义和措施的挑战。
Since the earliest days of the AIDS epidemic, clinicians have been concerned about the prevalence of depression among their patients. Epidemiologists, psychiatrists, psychologists, sociologists, and a broad array of other specialists have studied this topic, trying to determine the prevalence of depressive disorders and depressive symptoms as well as antecedents, correlates, and consequences. This review addresses the methodologic difficulties in determining depression prevalence, major findings regarding rates of disorder and correlates among different segments of the HIV community, effects of depression on HIV illness progression, psychopharmacologic and psychotherapeutic treatment findings, and behavioral effects of depression, such as its impact on medication adherence, employment, and risk behavior. Finally, the article summarizes international studies of depression prevalence in developing countries and the challenges regarding cross-national diagnostic definitions and measures.