Stepwise radical endoscopic resection versus radiofrequency ablation for Barrett's oesophagus with high-grade dysplasia or early cancer: a multicentre randomised trial

Stepwise radical endoscopic resection versus radiofrequency ablation for Barrett's oesophagus with high-grade dysplasia or early cancer: a multicentre randomised trial
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DOI：
10.1136/gut.2010.229310
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发表时间：
2011-06-01
期刊：
GUT
影响因子：
24.5
通讯作者：
Bergman, Jacques J. G. H. M.
Bergman, Jacques J. G. H. M.
中科院分区：
医学1区
文献类型：
--
作者：
van Vilsteren, Frederike G. I.;Pouw, Roos E.;Bergman, Jacques J. G. H. M.

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Objective After focal endoscopic resection (ER) of high-grade dysplasia (HGD) or early cancer (EC) in Barrett's oesophagus (BO), eradication of all remaining BO reduces the recurrence risk. The aim of this study was to compare the safety of stepwise radical ER (SRER) versus focal ER followed by radiofrequency ablation (RFA) for complete eradication of BO containing HGD/EC.Methods A multicentre randomised clinical trial was carried out in three tertiary centres. Patients with BO