A monoclonal antibody recognizing a cell surface antigen coded for by a gene on human chromosome 17

A monoclonal antibody recognizing a cell surface antigen coded for by a gene on human chromosome 17
复制标题

一种单克隆抗体,可识别由人类 17 号染色体上的基因编码的细胞表面抗原

DOI:
10.1111/j.1469-1809.1982.tb01584.x
复制
发表时间:
1982
影响因子:
1.9
通讯作者:
A. Tunnacliffe
A. Tunnacliffe
中科院分区:
生物学4区
文献类型:
--
作者:
Y. Bai;D. Sheer;L. Hiorns;R. Knowles;A. Tunnacliffe

文献摘要

参考文献

被引文献

相似文献

单克隆抗体 H207 是针对人 T 细胞衍生的急性淋巴细胞白血病系 HSB-2 产生的,可识别表观分子量为 125000 的抗原,该抗原由 17 号染色体上的 MIC6 基因编码。分配是基于与一组体细胞杂交体的反应模式。特别是,仅包含人类 17 号染色体或人类易位染色体 t(3;17) (3pter-3p11::17p11-17qter) 的两个杂交体分别结合 H207,而它们的回复体则没有。 H207 抗原具有普遍的组织分布,但在 B 细胞系中未发现,并且在某些 T 细胞系中也缺乏。
The monoclonal antibody, H207, raised against the human T‐cell‐derived acute lymphoblastic leukaemia line HSB‐2, recognizes an antigen of apparent molecular weight 125000 which is coded for by the gene, MIC6, on chromosome 17. Assignment was based on the pattern of reactivity with a panel of somatic cell hybrids. In particular, two hybrids containing only human chromosome 17 or a human translocation chromosome t(3;17) (3pter‐3p11::17p11–17qter) respectively bound H207, whilst their revertands did not. The H207 antigen has a general tissue distribution but is not found on B‐cell lines and is lacking from some T‐cell lines.
通过单克隆抗体 (HNK-1) 识别的人类 NK 和 K 细胞的分化抗原。
DOI: --
发表时间: 1981
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Abo,T;Balch,CM
通讯作者: Balch,CM