Measuring elimination of podoconiosis, endemicity classifications, case definition and targets: an international Delphi exercise.
Measuring elimination of podoconiosis, endemicity classifications, case definition and targets: an international Delphi exercise.
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DOI：
10.1093/inthealth/ihv043
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发表时间：
2015-09
影响因子：
2.5
通讯作者：
Davey G
中科院分区：
文献类型：
--
作者：
Deribe K;Wanji S;Shafi O;Muheki Tukahebwa E;Umulisa I;Davey G
脚足病是热带地区淋巴水肿的主要原因之一。尽管如此，目前还没有流行病分类或消除目标来监测干预措施的效果。本研究旨在建立病例定义和指标，用于评估脚足病的流行、消除和临床结果。本文描述了 28 名专家使用德尔菲技术的结果。制定了一份概述可能的病例定义、流行分类、消除目标和临床结果的调查问卷。调查问卷分两轮分发给从事脚足病和其他被忽视的热带病工作的专家。专家们评估了病例定义、流行病分类、消除目标和临床结果措施的重要性。中位数和众数用于描述专家回答的集中趋势。变异系数用于描述专家反应的分散程度。经过两轮德尔菲法，专家们就针对政策制定者和卫生工作者的脚足病流行、消除和临床结果评估的定义和指标达成了共识。基于两轮德尔菲调查，我们讨论了这种致残疾病的潜在指标和流行分类，以及在患病率最高的国家消除这种疾病所面临的持续挑战。达成共识将有助于提高消除脚足病工作的有效性并确保结果数据的可比性。
Podoconiosis is one of the major causes of lymphoedema in the tropics. Nonetheless, currently there are no endemicity classifications or elimination targets to monitor the effects of interventions. This study aimed at establishing case definitions and indicators that can be used to assess endemicity, elimination and clinical outcomes of podoconiosis. This paper describes the result of a Delphi technique used among 28 experts. A questionnaire outlining possible case definitions, endemicity classifications, elimination targets and clinical outcomes was developed. The questionnaire was distributed to experts working on podoconiosis and other neglected tropical diseases in two rounds. The experts rated the importance of case definitions, endemic classifications, elimination targets and the clinical outcome measures. Median and mode were used to describe the central tendency of expert responses. The coefficient of variation was used to describe the dispersals of expert responses. Consensus on definitions and indicators for assessing endemicity, elimination and clinical outcomes of podoconiosis directed at policy makers and health workers was achieved following the two rounds of Delphi approach among the experts. Based on the two Delphi rounds we discuss potential indicators and endemicity classification of this disabling disease, and the ongoing challenges to its elimination in countries with the highest prevalence. Consensus will help to increase effectiveness of podoconiosis elimination efforts and ensure comparability of outcome data.