ETIOLOGY AND TREATMENT OF ACUTE BACTERIAL-INFECTION OF THE EXTERNAL EYE
ETIOLOGY AND TREATMENT OF ACUTE BACTERIAL-INFECTION OF THE EXTERNAL EYE
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DOI：
10.1136/bjo.66.6.357
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发表时间：
1982-01-01
影响因子：
4.1
通讯作者：
MCGILL, JI
中科院分区：
文献类型：
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作者：
SEAL, DV;BARRETT, SP;MCGILL, JI
对738例急性细菌性结膜炎、角膜溃疡、睑缘炎、泪囊炎、放电槽患者的微生物菌群进行了调查。分离出的主要病原菌为金黄色葡萄球菌、肺炎链球菌和流感嗜血杆菌。草绿色链球菌与 1 岁以下患者的结膜炎有关。莫拉氏菌属仅被隔离 1 次。总体而言，40% 的标本与表皮葡萄球菌或混合皮肤菌群相关，这也发生在正常眼睛的培养物中。韦尔奇梭菌[C.产气荚膜杆菌]曾 3 次被分离出来，但与大疱或气性坏疽无关。总体耐药性最低的是氯霉素，为 6%，但没有一种抗生素对所有病原体都有效。庆大霉素仍然是治疗铜绿假单胞菌感染的首选抗生素。
The microbial flora of 738 patients with acute bacterial conjunctivitis, corneal ulceration, blepharitis, decryocystitis and discharging sockets was investigated. Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae were the main pathogens isolated. Viridans Streptococcus was associated with conjunctivitis in patients aged under 1 yr. Moraxella sp. was isolated on only 1 occasion. Overall, 40% of specimens were associated with Staphylococcus epidermidis or mixed skin flora, which also occurred with cultures of the normal eye. Clostridium welchii [C. perfringens] was isolated on 3 occasions, but was not associated with bullae or gas gangrene. The least overall resistance, of 6%, was to chloramphenicol, but no 1 antibiotic was effective against all pathogens. Gentamicin remains the antibiotic of choice for Pseudomonas aeruginosa infection.