Using a digital tool to detect early changes in everyday functioning in older adults: A pilot study of the Assessment of Smartphone Everyday Tasks (ASSET).
Using a digital tool to detect early changes in everyday functioning in older adults: A pilot study of the Assessment of Smartphone Everyday Tasks (ASSET).
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DOI：
10.1002/dad2.12506
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发表时间：
2023-10
影响因子：
5.3
通讯作者：
Marshall, Gad A
中科院分区：
文献类型：
--
作者：
Dubbelman, Mark A;Hall, Tia C;Levesque, Isabella M;Mimmack, Kayden J;Sikkes, Sietske A M;Fischer, Shira H;Rentz, Dorene M;Sperling, Reisa A;Papp, Kathryn V;Amariglio, Rebecca E;Marshall, Gad A
为了研究一种新的数字工具在临床前阿尔茨海默病中测量日常功能的实用性，我们试用了智能手机日常任务评估（ASSET）应用程序。46名受试者（50.3 ± 27.1岁; 67%女性; 20名未受损的年轻人，17名未受损的老年人，9名轻度认知受损）完成了7次ASSET。ASSET包括两个主要任务，模拟患者门户和日历。我们评估了ASSET的内部一致性、重测可靠性和用户体验。ASSET主要任务之间存在相关性（r = 0.75，95%可信区间[CI] = [0.58，0.86]）。ASSET患者门户网站上的表现与认知（r = 0.64，95% CI = [0.42，0.79]）和观察员日常功能评分（r = 0.57，95% CI = [0.24，0.79]）相关。重测信度良好（组内相关系数= 0.87，95%CI = [0.77，0.93]）。大多数参与者对他们使用ASSET的体验进行了中立或积极的评价。ASSET是一个很有前途的基于智能手机的日常功能数字评估。未来的研究可能会调查其在阿尔茨海默病早期诊断和治疗评估中的实用性。
To investigate the utility of a new digital tool for measuring everyday functioning in preclinical Alzheimer's disease, we piloted the Assessment of Smartphone Everyday Tasks (ASSET) application. Forty‐six participants (50.3 ± 27.1 years; 67% female; 20 young unimpaired, 17 old unimpaired, 9 mildly cognitively impaired) completed ASSET 7 times. ASSET comprises two main tasks, simulating a Patient Portal and a Calendar. We assessed ASSET's internal consistency, test–retest reliability, and user experience. ASSET main tasks correlated with each other (r = 0.75, 95% confidence interval [CI] = [0.58, 0.86]). Performance on ASSET's Patient Portal related to cognition (r = 0.64, 95% CI = [0.42, 0.79]) and observer ratings of everyday functioning (r = 0.57, 95% CI = [0.24, 0.79]). Test–retest reliability was good (intraclass correlation coefficient = 0.87, 95% CI = [0.77, 0.93]). Most participants rated their experience with ASSET neutrally or positively. ASSET is a promising smartphone‐based digital assessment of everyday functioning. Future studies may investigate its utility for early diagnosis and evaluation of treatment of Alzheimer's disease.