Short and Efficient Synthetic Route to Methyl α-Trioxacarcinoside B and Anomerically Activated Derivatives
Short and Efficient Synthetic Route to Methyl α-Trioxacarcinoside B and Anomerically Activated Derivatives
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DOI:
10.1021/ol202315m
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发表时间:
2011-10-21
期刊:
影响因子:
5.2
通讯作者:
Myers, Andrew G.
中科院分区:
文献类型:
--
作者:
Magauer, Thomas;Myers, Andrew G.
A 9-step synthetic route to the complex carbohydrate methyl alpha-trioxacarcinoside B from 2-acetylfuran is described. Anomerically activated forms, including 1-phenylthio, 1-O-(4'-pentenyl), 1-fluoro, and 1-O-acetyl derivatives are also prepared.