Negative Urgency Linked to Craving and Substance Use Among Adults on Buprenorphine or Methadone
Negative Urgency Linked to Craving and Substance Use Among Adults on Buprenorphine or Methadone
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DOI：
10.1007/s11414-023-09845-4
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发表时间：
2023-07-06
影响因子：
1.9
通讯作者：
Sikdar，Siddhartha
中科院分区：
文献类型：
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作者：
Goncalves，Stefanie F.;Izquierdo，Alyssa M.;Sikdar，Siddhartha
尽管药物辅助治疗（MAT）有效，但接受MAT的成年人会产生阿片类药物的渴望，并参与非阿片类非法物质的使用，这会增加复发和过量的风险。目前的研究探讨了消极紧迫感（定义为对强烈的负面情绪做出冲动反应的倾向）是否是阿片类药物渴望和非阿片类药物非法使用的风险因素。从在线物质使用论坛招募了58名接受MAT（丁丙诺啡或美沙酮）的成年人（主要是白色顺性别女性），并要求他们完成关于消极紧迫感（UPPS-P冲动行为量表）、过去3个月阿片类药物渴望（辅助酒精、吸烟和物质参与筛选测试）和非阿片类非法物质使用（例如，安非他明、可卡因、苯二氮卓类）。结果显示，消极紧迫感与过去3个月的阿片类药物渴望以及过去一个月的非法兴奋剂使用（而不是苯二氮卓类药物使用）有关。这些结果可能表明，负紧迫感高的人将受益于在MAT期间接受额外的干预。
Despite the effectiveness of medication-assisted treatment (MAT), adults receiving MAT experience opioid cravings and engage in non-opioid illicit substance use that increases the risk of relapse and overdose. The current study examines whether negative urgency, defined as the tendency to act impulsively in response to intense negative emotion, is a risk factor for opioid cravings and non-opioid illicit substance use. Fifty-eight adults (predominately White cis-gender females) receiving MAT (with buprenorphine or methadone) were recruited from online substance use forums and asked to complete self-report questionnaires on negative urgency (UPPS-P Impulsive Behavior Scale), past 3-month opioid cravings (ASSIST—Alcohol, Smoking, and Substance Involvement Screening Test), and non-opioid illicit substance use (e.g., amphetamines, cocaine, benzodiazepines). Results revealed that negative urgency was associated with past 3-month opioid cravings, as well as past month illicit stimulant use (not benzodiazepine use). These results may indicate that individuals high in negative urgency would benefit from receiving extra intervention during MAT.