Disassembly Control of Saccharide-Based Amphiphiles Driven by Electrostatic Repulsion.
Disassembly Control of Saccharide-Based Amphiphiles Driven by Electrostatic Repulsion.
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DOI：
10.1021/acs.langmuir.6b04360
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发表时间：
2017-03
期刊：
影响因子：
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通讯作者：
Taihei Yamada;K. Kokado;K. Sada
中科院分区：
文献类型：
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作者：
Taihei Yamada;K. Kokado;K. Sada
根据静电排斥拆分设计，利用铜催化的点击反应合成了由亲脂性离子部分和亲水性糖部分组成的新型两亲分子，并研究了它们在水和氯仿中的分子组装.在每种情况下，两亲物都表现出与常规两亲物相反的分子取向。电位测量表明亲脂性离子部分暴露在氯仿中。两亲物中疏溶剂部分的大小决定了组装结构的大小;也就是说，在水中，这些束缚不同长度的糖部分的两亲物表现出几乎相同的组装大小，而在氯仿中，组装大小取决于两亲物中糖部分的长度。
According to the design of disassembly using electrostatic repulsion, novel amphiphiles consisting of a lipophilic ion part and a hydrophilic saccharide part were synthesized via the facile copper-catalyzed click reaction, and their molecular assemblies in water and chloroform were studied. The amphiphiles exhibited a molecular orientation opposite to that of the conventional amphiphiles in each case. ζ Potential measurements indicated that the lipophilic ion part is exposed outside in chloroform. The size of a solvophobic part in the amphiphiles dominates the size of an assembling structure; that is, in water, these amphiphiles tethering different lengths of the saccharide part exhibited almost identical assembling size, whereas in chloroform, the size depends on the length of the saccharide part in the amphiphiles.