Correlation Between Kinesia System Assessments and Clinical Tremor Scores in Patients with Essential Tremor
Correlation Between Kinesia System Assessments and Clinical Tremor Scores in Patients with Essential Tremor
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DOI：
10.1002/mds.23201
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发表时间：
2010-09-15
影响因子：
8.6
通讯作者：
Jankovic, Joseph
中科院分区：
文献类型：
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作者：
Mostile, Giovanni;Giuffrida, Joseph P.;Jankovic, Joseph
本研究的主要目的是确定特发性震颤评定量表（TETRAS）评分是否与使用Kinesia（TM）（CleveMed）系统对特发性震颤（ET）患者进行的定量评估相关。在贝勒医学院帕金森病中心和运动障碍诊所连续评估和诊断为ET的患者参加了这项研究。Kinesia便携式设备被连接到手腕上，受试者被指示将手臂伸直，然后触摸鼻子，同时数据被无线传输到计算机。使用特定的TETRAS项目对放置系统的手臂上的受试者进行评级。使用临床评分和客观运动数据参数的对数值为每个任务构建线性回归模型，以计算Kinesia评分。20例受试者接受了完整的临床TETRAS和Kinesia定量评估。TETRAS临床评分与预测的姿势性震颤（r = 0.738; P < 0.001）和动力性震颤（r = 0.57; P = 0.009）的Kinesia定量变量显著相关。因此，我们得出结论，Kinesia系统可能与标准临床评估相结合，在ET的定量评估中具有实用性。(C)2010年运动障碍协会
The primary aim of this study was to determine whether scores on The Essential Tremor Rating Assessment Scale (TETRAS) correlate with quantitative assessments using the Kinesia (TM) (CleveMed) system in patients with essential tremor (ET). Patients sequentially evaluated and diagnosed with ET at the Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine were enrolled in the study. The Kinesia portable device was attached to the wrist and subjects were instructed to hold their arms in an outstretched position and then touch their nose while data were wirelessly transmitted to a computer. Subjects were rated on the arm where the system was placed using specific TETRAS items. A linear regression model was constructed for each task using the logarithmic values of both clinical scores and objective motion data parameters to compute a Kinesia score. Twenty subjects underwent complete clinical TETRAS and Kinesia quantitative assessments. TETRAS clinical scores significantly correlated with predicted Kinesia quantitative variables for postural (r = 0.738; P < 0.001) and kinetic (r = 0.57; P = 0.009) tremor. We conclude that the Kinesia system may, therefore, have a utility in quantitative assessments of ET when combined with standard clinical assessment. (C) 2010 Movement Disorder Society