Vasospastic angina in a 13-year-old female patient whose only symptom was toothache

Vasospastic angina in a 13-year-old female patient whose only symptom was toothache
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DOI:
10.1007/s00246-006-1374-4
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发表时间:
2007-02-01
影响因子:
1.6
通讯作者:
Harigaya, Kenichi
Harigaya, Kenichi
中科院分区:
医学4区
文献类型:
--
作者:
Okajima, Yoshitomo;Hirai, Aizan;Harigaya, Kenichi

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尸检证实一名 13 岁女性患者患有血管痉挛性心绞痛。患者唯一的症状是反复牙痛,从她10岁时开始出现。 2000年11月,她在我们医疗中心接受评估;然而,所有检查均被判定为正常。六个月后,她牙痛严重。症状好转后,她第二天早上就去上学了。她在学校失去知觉,接受心肺复苏,但未能苏醒。尸检时,她的三支冠状血管内膜明显增生,左心室侧壁多发局灶性心肌梗死。患者唯一的临床症状是牙痛,但没有一个医生意识到这是由心绞痛引起的。血管痉挛性心绞痛始于年轻时,是青少年猝死的原因之一。
Vasospastic angina was confirmed in a 13-year-old female patient at autopsy. The patient's only symptom was recurrent toothache, which began when she was 10 years old. In November 2000, she was evaluated at our medical center; however, all examinations were judged normal. Six months later, she suffered a severe toothache. She went to school the next morning after the symptoms improved. She lost consciousness at school and was given cardiopulmonary resuscitation but could not be revived. At autopsy, her three coronary vessels showed marked intimal hyperplasia, and multiple focal myocardial infarctions were observed in the lateral wall of the left ventricle. The patient's only clinical symptom was toothache and none of the physicians realized that this was caused by angina. Vasospastic angina begins at a young age and is one of the causes of sudden death in adolescents.