Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19
Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19
复制标题
轻度 COVID-19 患者心血管负担与重症监护需求之间的关联。
DOI：
10.1155/2020/9059562
复制
发表时间：
2020-08-16
影响因子：
3.1
通讯作者：
Zhou, Shenghua
中科院分区：
文献类型：
--
作者：
Tai, Shi;Tang, Jianjun;Zhou, Shenghua
背景关于心血管（CV）疾病对2019年轻度冠状病毒病（COVID-19）患者疾病进展的影响的信息有限。本研究评估了轻度COVID-19患者的基础CV疾病与疾病进展的相关性。主要结局为因COVID-19疾病进展需要转至指定医院接受重症监护。将患者分为有和无CV疾病以及稳定和重症监护组。在332名轻度COVID-19患者中，中位年龄为51岁（IQR，40-59岁），200名（61.2%）为女性。在48例（14.5%）CV疾病患者中，23例（47.9%）进展为重度疾病状态，需要重症监护。与无心血管疾病的患者相比，心血管疾病患者年龄更大，更容易出现疲劳、胸闷和肌痛。患有CV疾病的患者需要重症监护的比例明显高于无CV疾病的患者（47.92% vs. 12.4%;P
Background. Information regarding the impact of cardiovascular (CV) conditions on disease progression among patients with mild coronavirus disease 2019 (COVID-19) is limited.Methods. This study evaluated the association of underlying CV conditions with disease progression in patients with mild COVID-19. The primary outcome was the need to be transferred to the designated hospital for intensive care due to COVID-19 disease progression. The patients were divided into with and without CV conditions as well as stable and intensive care groups.Results. Of the 332 patients with mild COVID-19, the median age was 51 years (IQR, 40-59 years), and 200 (61.2%) were female. Of the 48 (14.5%) patients with CV conditions, 23 (47.9%) progressed to severe disease status and required intensive care. Compared with patients without CV conditions, patients with CV conditions were older and more likely to have fatigue, chest tightness, and myalgia. The rate of requiring intensive care was significantly higher among patients with CV conditions than in patients without CV conditions (47.92% vs. 12.4%;P