Naphthalenones from a Perenniporia sp Inhabiting the Larva of a Phytophagous Weevil, Euops chinesis
Naphthalenones from a Perenniporia sp Inhabiting the Larva of a Phytophagous Weevil, Euops chinesis
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DOI：
10.1021/np300263u
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发表时间：
2012-07-01
影响因子：
5.1
通讯作者：
Che, Yongsheng
中科院分区：
文献类型：
--
作者：
Feng, Yu;Wang, Lin;Che, Yongsheng
新的萘酮衍生物perenniporides A-D（1-4）是从寄生于中国黄姑草（Euops chinesis）幼虫的真菌Perenniporia sp.的固体培养物中分离得到的。化合物1-4的结构经核磁共振实验初步确定，化合物1的结构经X射线晶体学确证。化合物1和2的绝对构型由电子圆二色性（ECD）计算确定，化合物3中C-10叔醇的绝对构型由原位形成的[Rh-2（OCOCF 3）（4）]配合物的CD数据推断，并得到ECD数据的支持。化合物1对5种植物病原菌具有抑菌活性。
The new naphthalenone derivatives perenniporides A-D (1-4) were isolated from solid cultures of a fungus Perenniporia sp. inhabiting the larva of Euops chinesis, a phytophagous weevil with high host specificity to the medicinal plant Fallopia japonica. The structures of 1-4 were elucidated primarily by NMR experiments, and 1 was confirmed by X-ray crystallography. The absolute configuration of 1 and 2 was assigned by electronic circular dichroism (ECD) calculations, whereas that of the C-10 tertiary alcohol in 3 was deduced via the CD data of the in situ formed [Rh-2(OCOCF3)(4)] complex and supported by the ECD data Compound 1 showed antifungal activity against five plant pathogens.