TRAUMA-INDUCED PROTEIN IN RAT-TISSUES - A PHYSIOLOGICAL-ROLE FOR A HEAT-SHOCK PROTEIN

TRAUMA-INDUCED PROTEIN IN RAT-TISSUES - A PHYSIOLOGICAL-ROLE FOR A HEAT-SHOCK PROTEIN
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DOI:
10.1126/science.7280681
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发表时间:
1981-01-01
期刊:
影响因子:
56.9
通讯作者:
WHITE, FP
WHITE, FP
中科院分区:
综合性期刊1区
文献类型:
--
作者:
CURRIE, RW;WHITE, FP

文献摘要

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Hyperthermic shock induces the synthesis of a novel protein (P71) in many rat tissues in vivo. In incubated rat tissue slices P71 is the major protein synthesized even though it is undetectable in the tissues of a normal, unstressed rat. P71 is a heat shock protein, and it may be induced in vivo by stimuli other than hyperthermia. Caution must be used in studies of protein synthesis in tissue explants, since the pattern of proteins synthesized by rat tissue slices is characteristic of stressed tissue.