The prevalence and determinants of short stature in HIV-infected children.
The prevalence and determinants of short stature in HIV-infected children.
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DOI：
10.1177/2325957414531621
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发表时间：
2014-11-01
影响因子：
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通讯作者：
Ahmed, Syed Faisal
中科院分区：
文献类型：
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作者：
Joel, Dipesalema R;Mabikwa, Vincent;Ahmed, Syed Faisal
背景：据报道，感染艾滋病毒的儿童通常身材矮小。本研究的目的是评估艾滋病毒流行环境中与艾滋病毒相关的身材矮小的患病率。方法：通过回顾性审查电子病历获得数据。患者被分为不同的临床类别。对于每个类别，确定年龄别身高 Z 评分小于 -2 标准差 [SD] 和小于 -3 SD 的患者比例。 结果：身材矮小（小于 -2 SD）的患病率为 28.4%。 CD4 百分比为 400 拷贝/mL（OR 2.64，CI 1.27-5.38，P = .008）且依从性差时，更可能出现严重身材矮小（小于 -3 SD）（
BACKGROUND: Children with HIV infection are often reported to be short. The aim of this study was to assess the prevalence of HIV-associated short stature in HIV endemic setting.METHODS: Data were obtained by retrospective review of the electronic medical records. Patients were grouped into various clinical categories. For each category, the proportion of patients with height-for-age Z score of less than -2 standard deviation [SD] and of less than -3 SD was determined.RESULTS: The prevalence of short stature (less than -2 SD) was 28.4%. Severe short stature (less than -3 SD) is more likely with percentage of CD4 400 copies/mL (OR 2.64, CI 1.27-5.38, P = .008) and poor adherence (