Glistenings on Intraocular Lenses in Healthy Eyes: Effects and Associations
Glistenings on Intraocular Lenses in Healthy Eyes: Effects and Associations
复制标题
DOI：
10.3928/1081597x-20110725-01
复制
发表时间：
2011-12-01
影响因子：
2.4
通讯作者：
Orignac, Isabelle
中科院分区：
文献类型：
--
作者：
Colin, Joseph;Orignac, Isabelle
目的：评估 AcrySof（爱尔康实验室公司）人工晶状体 (IOL) 的反光，量化反光对健康眼睛患者视功能的影响，并调查反光是否与人口统计学或晶状体特征相关。 方法：对一系列连续健康眼睛的病例档案进行回顾性分析。研究了主观反光等级与以下参数的关联：对比敏感度、矫正远视力 (CDVA)、眼内光散射（通过 C-Quant [Oculus Optikgerate GmbH] 测量）、后囊混浊、人口统计特征、晶状体屈光力和人工晶状体眼持续时间。将主观分级方法与基于客观软件的反光定量进行比较。 结果：研究队列包括 65 名患者的 97 只眼睛，平均年龄为 65 +/- 11 岁。平均随访时间为 18 +/- 17 个月。尽管研究设计对此结果的可信度有限，但闪光等级并不随人工晶体眼持续时间的变化而变化 (P=.19)。闪光等级与晶状体屈光度 (P=.41)、眼内光散射 (P=.31)、logMAR CDVA (P=.64)、任何空间频率下的对比敏感度（所有 P >=.22）或任何其他正在研究的参数没有关联。基于软件的评估证实了主观分级方法的有效性：闪光等级与空泡/mm(2)相关（P
PURPOSE: To assess glistenings in AcrySof (Alcon Laboratories Inc) intraocular lenses (IOLs), to quantify any effects of glistenings on the visual function of patients with healthy eyes, and to investigate whether glistenings were associated with demographic or lens characteristics.METHODS: Case files from a consecutive series of healthy eyes were retrospectively analyzed. Subjective glistening grades were investigated for associations with the following parameters: contrast sensitivity, corrected distance visual acuity (CDVA), intraocular light scattering (measured by C-Quant [Oculus Optikgerate GmbH]), posterior capsule opacification, demographic characteristics, lens power, and duration of pseudophakia. The subjective grading method was compared to objective software-based quantitation of glistenings.RESULTS: The study cohort included 97 eyes from 65 patients with a mean age of 65 +/- 11 years. Mean follow-up was 18 +/- 17 months. Glistening grades did not vary by duration of pseudophakia (P=.19), although study design limited confidence in this result. Glistening grades had no associations with lens power (P=.41), intraocular light scattering (P=.31), logMAR CDVA (P=.64), contrast sensitivity at any spatial frequency (all P >=.22), or with any other parameter under investigation. The software-based assessment confirmed the validity of the subjective grading method: glistening grades correlated with vacuoles/mm(2) (P