A Web Interface for the Quantification of Microtubule Dynamics.
A Web Interface for the Quantification of Microtubule Dynamics.
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用于量化微管动力学的 Web 界面。
DOI：
10.1109/bibmw.2011.6112376
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Wang,MayD
中科院分区：
文献类型：
--
作者：
Kong,KoonYin;Marcus,AdamI;Giaanakakou,Paraskevi;Wang,MayD
我们提出了一个网络接口，使研究人员能够在线量化和分析微管共聚焦图像。大多数微管共聚焦图像的分析是使用非常简单的软件或工具手动进行的。分析结果以不同的风格和格式存储在每个协作者的本地。这限制了不同研究方之间合作时数据和结果的共享。Web界面为用户在线处理数据提供了一种简单的方法。它还允许不同参与团体之间轻松共享数据和结果。界面的分析工作流程与现有手动协议相似。我们展示了图像处理算法在当前工作流程中的集成，以帮助分析。我们的设计还允许集成新的自动分析算法和模块，以重新评估现有数据。该接口可以为新的自动化算法提供验证平台，并允许来自不同位置的微管图像分析的协作。
We propose a web interface that allows researchers to quantify and analyze microtubule confocal images online. Most analyses of microtubule confocal images are performed manually using very simple software or tools. Analysis results are stored locally within each collaborator with different styles and formats. This has limited the sharing of data and results when collaborating among different research parties. A web interface provides a simple way for users to process data online. It also allows easy sharing of both data and results among different participating groups. Analysis workflow of the interface is made similar to existing manual protocols. We demonstrate the integration of image processing algorithm in the current workflow to aid the analysis. Our design also allows integration of novel automated analysis algorithms and modules to re-evaluate existing data. This interface can provide a validation platform for new automated algorithm and allow collaboration on microtubule image analysis from different locations.