THE 20/20 EYE IN MULTIPLE-SCLEROSIS
THE 20/20 EYE IN MULTIPLE-SCLEROSIS
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DOI：
10.1212/wnl.33.8.1015
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发表时间：
1983-01-01
期刊：
影响因子：
9.9
通讯作者：
WEISS, PA
中科院分区：
文献类型：
--
作者：
KUPERSMITH, MJ;NELSON, JI;WEISS, PA
使用临床和电生理测量，对患有多发性硬化症、20/20 Snellen视力和无视神经炎病史的患者的视路进行了评估。瞬态视觉诱发电位（VEP）潜伏期延迟者占38%，眼间潜伏期差异常者占67%。对比VEP异常者占46%。78%的患者对比敏感度的心理物理测定异常。只有17%的患者有色觉障碍，36%有传入瞳孔异常，59%有视神经苍白或神经纤维层丢失。在显示这些患者的视觉功能障碍方面，心理物理对比评估和VEP研究上级其他临床评估。
Using clinical and electrophysiologic measures, the visual pathway of patients who had multiple sclerosis, 20/20 Snellen acuity and no history of optic neuritis were evaluated. Delayed latencies were found in the transient visual evoked potentials (VEP) of 38% of the patients, and interocular latency differences were abnormal in 67%. Contrast VEP were abnormal in 46%. Psychophysical determinations of contrast sensitivity were abnormal in 78%. Only 17% of the patients had dyschromatopsia, 36% had afferent pupillary abnormalities and 59% had optic nerve pallor or nerve fiber layer loss. Psychophysical contrast evaluations and VEP studies were superior to other clinical evaluations in demonstrating visual dysfunction in these patients.