Simulation study comparing high-purity germanium and cadmium zinc telluride detectors for breast imaging.
Simulation study comparing high-purity germanium and cadmium zinc telluride detectors for breast imaging.
复制标题
比较用于乳腺成像的高纯度锗和碲化镉锌探测器的模拟研究。
DOI：
10.1088/0031-9155/59/22/7059
复制
发表时间：
2014
影响因子：
3.5
通讯作者：
Peterson,TE
中科院分区：
文献类型：
--
作者：
Campbell,DL;Peterson,TE
我们进行了模拟，以比较高纯度锗（HPGe）和碲锌镉（CZT）系统在140 keV下分别具有1%和3.8%能量分辨率的乳腺癌检测的潜在成像性能。使用蒙特卡罗N粒子（MCNP 5）模拟包，我们建模5 mm厚的CZT和10 mm厚的HPGe探测器与相同的平行孔准直器的乳房/躯干体模的成像。模拟的能谱生成，并创建平面图像的各种能量窗口周围的140 keV的峰值。相对灵敏度和散射和躯干分数与肿瘤对比度和信噪比（SNR）一起计算沿着。模拟显示，与使用− 5%/+ 10%能量窗口的可比CZT系统相比，使用HPGe系统的±1.25%能量窗口可以更好地抑制躯干背景和小角度散射光子。两种系统提供了统计学上相似的对比度和SNR，HPGe提供了更高的相对灵敏度。降低HPGe图像的计数以匹配CZT计数密度仍然在HPGe和CZT之间产生等同的对比度。因此，HPGe系统在获取相等的成像时间时可以在较低的注入放射性水平下提供等同的乳房成像能力。
We conducted simulations to compare the potential imaging performance for breast cancer detection with High-Purity Germanium (HPGe) and Cadmium Zinc Telluride (CZT) systems with 1% and 3.8% energy resolution at 140 keV, respectively. Using the Monte Carlo N-Particle (MCNP5) simulation package, we modelled both 5 mm-thick CZT and 10 mm-thick HPGe detectors with the same parallel-hole collimator for the imaging of a breast/torso phantom. Simulated energy spectra were generated, and planar images were created for various energy windows around the 140 keV photopeak. Relative sensitivity and scatter and the torso fractions were calculated along with tumour contrast and signal-to-noise ratios (SNR). Simulations showed that utilizing a±1.25% energy window with an HPGe system better suppressed torso background and small-angle scattered photons than a comparable CZT system using a− 5%/+ 10% energy window. Both systems provided statistically similar contrast and SNR, with HPGe providing higher relative sensitivity. Lowering the counts of HPGe images to match CZT count density still yielded equivalent contrast between HPGe and CZT. Thus, an HPGe system may provide equivalent breast imaging capability at lower injected radioactivity levels when acquiring for equal imaging time.