METABOLISM OF TYROSINE-O-PHOSPHATE IN DROSOPHILA
METABOLISM OF TYROSINE-O-PHOSPHATE IN DROSOPHILA
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DOI：
10.1016/0003-9861(69)90388-9
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发表时间：
1969-01-01
影响因子：
3.9
通讯作者：
MITCHELL, HK
中科院分区：
文献类型：
--
作者：
LUNAN, KD;MITCHELL, HK
本文研究了酪氨酸-O-磷酸作为果蝇蛹壳鞣制底物的作用。从14 C酪氨酸标记实验结合多巴脱羧酶的研究，它似乎很可能是酪氨酸-O-磷酸水解之前，参与鞣制反应。随后的代谢可能是通过多巴胺和N-乙酰-多巴胺，如已描述的丽蝇属，虽然这些中间产物不积累在果蝇。在此基础上，酪氨酸磷酸可能仅代表相对惰性的酪氨酸储库。然而，其他功能，如在运输中的作用仍然是可能的。
The role of tyrosine-O-phosphate as a substrate for tanning of the pupal case ofDrosophilahas been examined. From14C tyrosine label experiments combined with studies on dopa decarboxylase it appears likely that tyrosine-O-phosphate is hydrolyzed prior to participation in the tanning reaction. Subsequent metabolism may be through dopamine andN-acetyl-dopamine, as has been described forCalliphora, although these intermediates are not accumulated inDrosophila. On this basis the tyrosine phosphate may represent only a relatively inert tyrosine reservoir. However, other functions such as a role in transport remain as possibilities.