Cohort Life Tables by Smoking Status, Removing Lung Cancer as a Cause of Death

Cohort Life Tables by Smoking Status, Removing Lung Cancer as a Cause of Death
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DOI:
10.1111/j.1539-6924.2011.01662.x
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发表时间:
2012-08-01
期刊:
影响因子:
3.8
通讯作者:
Burns, David M.
Burns, David M.
中科院分区:
医学3区
文献类型:
--
作者:
Rosenberg, Marjorie A.;Feuer, Eric J.;Burns, David M.

文献摘要

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本研究的目的是通过吸烟状况制定生命表,消除肺癌这一死因。这些生命表是比较肺癌治疗或干预措施有效性的研究的输入,并提供了一种量化肺癌以外原因导致死亡的时间的方法。该研究结合了精算和统计平滑方法以及多个来源的数据,按照吸烟状况、出生队列、单岁和性别制定了单独的生命表。对于当前吸烟者,根据出生队列每天吸烟的平均数量,制定了按吸烟五分位数划分的单独生命表。最终产品是创建六张男性非肺癌生命表和六张女性生命表:五个当前吸烟者五分位数和一个从不吸烟者五分位数。前吸烟者的表格是基于戒烟前当前吸烟者五分位数和从不吸烟者概率的适当表格的线性组合,加上戒烟年龄和戒烟后时间的附加协变量。
The purpose of this study was to develop life tables by smoking status removing lung cancer as a cause of death. These life tables are inputs to studies that compare the effectiveness of lung cancer treatments or interventions, and provide a way to quantify time until death from causes other than lung cancer. The study combined actuarial and statistical smoothing methods, as well as data from multiple sources, to develop separate life tables by smoking status, birth cohort, by single year of age, and by sex. For current smokers, separate life tables by smoking quintiles were developed based on the average number of cigarettes smoked per day by birth cohort. The end product is the creation of six non-lung-cancer life tables for males and six tables for females: five current smoker quintiles and one for never smokers. Tables for former smokers are linear combinations of the appropriate table based on the current smoker quintile before quitting smoking and the never smoker probabilities, plus added covariates for the smoking quit age and time since quitting.