Ultrasound-mediated oxygen delivery from chitosan nanobubbles

Ultrasound-mediated oxygen delivery from chitosan nanobubbles
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DOI:
10.1016/j.ijpharm.2009.05.058
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发表时间:
2009-08-13
影响因子:
5.8
通讯作者:
Guiot, Caterina
Guiot, Caterina
中科院分区:
医学2区
文献类型:
--
作者:
Cavalli, Roberta;Bisazza, Agnese;Guiot, Caterina

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超声(US)能量结合充气微泡已用于医学成像多年。本研究调查了载氧壳聚糖气泡在存在或不存在US的情况下交换氧气的能力。超声处理增强了氧气输送,超声的频率和持续时间都影响了交换动力学。(C)2009 Elsevier B.V.保留所有权利。
Ultrasound (US) energy combined with gas-filled microbubbles has been used for several years in medical imaging. This study investigated the ability of oxygen-loaded chitosan bubbles to exchange oxygen in the presence or in the absence of US. Oxygen delivery is enhanced by sonication and both frequency and time duration of US affected the exchange kinetics. (C) 2009 Elsevier B.V. All rights reserved.