Inorganic nanoporous membranes for immunoisolated cell-based drug delivery.
Inorganic nanoporous membranes for immunoisolated cell-based drug delivery.
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DOI：
10.1007/978-1-4419-5786-3_10
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发表时间：
2010
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Materials advances enabled by nanotechnology have brought about promising approaches to improve the encapsulation mechanism for immunoisolated cell-based drug delivery. Cell-based drug delivery is a promising treatment for many diseases but has thus far achieved only limited clinical success. Treatment of insulin dependent diabetes mellitus (IDDM) by transplantation of pancreatic β-cells represents the most anticipated application of cell-based drug delivery technology. This review outlines the challenges involved with maintaining transplanted cell viability and discusses how inorganic nanoporous membranes may be useful in achieving clinical success.
