Self-reported side-effects associated with use of dietary supplements in an armed forces population
Self-reported side-effects associated with use of dietary supplements in an armed forces population
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DOI：
10.1002/dta.1905
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发表时间：
2016-03-01
影响因子：
2.9
通讯作者：
Lieberman, Harris R.
中科院分区：
文献类型：
--
作者：
Austin, Krista G.;Farina, Emily K.;Lieberman, Harris R.
大约60%-70%的武装部队人员每周至少消费一次膳食补充剂(DS)，有许多关于DS使用者发生严重不良事件的报告。本研究采用纸笔调查的方法，对4400名武装部队人员的DS使用模式和自我报告的副作用进行了评估。使用多变量Logistic回归来检验DS的使用模式和自我报告的副作用之间的关系。69%的受访人员报告使用DS。7%的DS使用者报告经历了异常心跳、6%的震颤、5%的胃痛、3%的头晕和3%的麻木/刺痛，他们认为这些症状与DS的使用有关。在对其他DS类别、总补充剂使用量和人口统计学特征进行调整后，蛋白质补充剂使用者比非使用者更有可能报告麻木/刺痛；联合产品使用者更有可能报告经历异常心跳、胃痛、头晕、震颤和麻木/刺痛；而据称是类固醇类似物的使用者更有可能报告头晕。每周使用一种以上的DS与报告副作用的可能性增加相关。体重指数较高的受访者报告副作用的可能性更大。有必要进行进一步的研究，以确定与多次使用DS和某些DS类别相关的自我报告副作用是否会影响服役人员的长期健康或表现。使用这样的调查对军人人群进行监测，可能会提供一种方法，在DS在平民人口中显现之前检测出DS的不良健康事件。版权所有(C)2015 John Wiley&Sons，Ltd.
Approximately 60-70% of Armed Forces personnel consume a dietary supplement (DS) at least once a week and there have been numerous reports of severe adverse events among DS users. This study assessed patterns of DS use and self-reported side-effects among 4400 Armed Forces personnel using a paper-and-pencil survey. Multivariable logistic regression was used to examine associations between patterns of DS use and self-reported side-effects. Sixty-nine percent of personnel surveyed reported using a DS. Seven percent of DS users reported experiencing abnormal heart beats, 6% tremors, 5% stomach pain, 3% dizziness, and 3% numbness/tingling and they believed these symptoms were associated with the use of DS. After adjustment for use of other DS classes, total supplement use, and demographic characteristics, protein supplement users were more likely than non-users to report numbness/tingling; combination product users were more likely to report experiencing abnormal heart beats, stomach pain, dizziness, tremors, and numbness/tingling; and users of purported steroid analogues were more likely to report dizziness. Use of more than one DS per week was associated with an increased likelihood of reporting side-effects. Respondents with a higher body mass index were more likely to report side-effects. Further research is necessary to determine whether self-reported side-effects associated with multiple DS use and some DS classes impact the long-term health or performance of service members. Surveillance of military populations using surveys like this one may provide a method for detecting adverse health events of DS before they are apparent in the civilian population. Copyright (c) 2015 John Wiley & Sons, Ltd.