Controlling Electron Rebound Within Four-Base Pi-Stacks in Z-DNA by Changing Sugar Moiety from Deoxy- to Ribonucleotide
Controlling Electron Rebound Within Four-Base Pi-Stacks in Z-DNA by Changing Sugar Moiety from Deoxy- to Ribonucleotide
复制标题
通过将糖部分从脱氧核苷酸改为核糖核苷酸来控制 Z-DNA 中四碱基 Pi 堆栈内的电子反弹
DOI：
10.1002/chem.201303930
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
H.
中科院分区：
文献类型：
--
作者：
Sannohe;Y.; Kizaki;S.; Kanesato;S.;Fujiwara;A.;Morinaga;H.; Tashiro;R.;Sugiyama;H.
通过DNA的电荷转移是非常感兴趣的，因为DNA是纳米电子传感器和设备的构建块的潜力。5-卤代尿嘧啶的光化学反应已被用于探测沿着DNA的电荷转移过程。我们之前报道了5-溴尿嘧啶在Z-DNA中的四个碱基π-堆叠内的光化学反应后的独特电荷转移。在这项研究中，我们将鸟苷而不是脱氧鸟苷掺入到Z-DNA中，并发现电子转移通过四碱基π堆叠以不同的机制发生。
Charge transfer through DNA is of great interest because of the potential of DNA to be a building block for nanoelectronic sensors and devices. The photochemical reaction of 5‐halouracil has been used for probing charge‐transfer processes along DNA. We previously reported on unique charge transfer following photochemical reaction of 5‐bromouracil within four‐base π‐stacks in Z‐DNA. In this study, we incorporated a guanosine instead of a deoxyguanosine into Z‐DNA, and found that electron transfer occurs in a different mechanism through four‐base π‐stacks.