Quality assurance of a system for improved target localization and patient set-up that combines real-time infrared tracking and stereoscopic X-ray imaging
Quality assurance of a system for improved target localization and patient set-up that combines real-time infrared tracking and stereoscopic X-ray imaging
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DOI：
10.1016/s0167-8140(02)00385-7
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发表时间：
2003-04-01
影响因子：
5.7
通讯作者：
Storme, G
中科院分区：
文献类型：
--
作者：
Verellen, D;Soete, G;Storme, G
背景和目的：本研究的目的是调查一个原型的X射线成像工具的位置精度结合一个实时的红外跟踪设备，允许自动化的病人设置在三维。材料和方法：原型的X射线成像工具已被集成与商业发布的实时红外跟踪设备。该系统由两个安装在天花板上的X射线管和一个位于中心的非晶硅探测器组成，已开发用于在治疗前从治疗室外自动定位患者。支持两个主要功能：（a）实际治疗图像与代表所需位置的数字重建X线照片（DRR）的自动融合;（B）植入的不透射线标记的匹配。测量已知的平移（最大30.0 mm）和旋转（最大4.0 °）的三维设置错误，以及隐藏的目标测试已经在拟人phantomorphic phantome.Results：该系统的精度可以表示与平均三维位移矢量，其中产生的DRR和X射线图像的融合0.6 mm（与总SD为0.9 mm）。已知平移误差和计算值之间的平均偏差在-0.3至0.6 mm之间变化，标准偏差在0.6-1.2 mm范围内。标记匹配算法产生的三维不确定度为0.3 mm。（总体SD：0.4 mm），平均值范围为0.0至0.3 mm，标准差范围为0.3至0.4圈。结论：与实时红外跟踪装置集成的立体X射线成像装置代表一种定位工具，其允许在可接受的时间范围内实现腹部和盆腔病变的适形放射治疗所需的几何精度。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
Background and purpose: The aim of this study is to investigate the positional accuracy of a prototype X-ray imaging tool in combination with a real-time infrared tracking device allowing automated patient set-up in three dimensions.Material and methods: A prototype X-ray imaging tool has been integrated with a commercially released real-time infrared tracking device. The system, consisting of two X-ray tubes mounted to the ceiling and a centrally located amorphous silicon detector has been developed for automated patient positioning from outside the treatment room prior to treatment. Two major functions are supported: (a) automated fusion of the actual treatment images with digitally reconstructed radiographs (DRRs) representing the desired position; (b) matching of implanted radio opaque markers. Measurements of known translational (up to 30.0 mm) and rotational (up to 4.0degrees) set-up errors in three dimensions as well as hidden target tests have been performed on anthropomorphic phantoms.Results: The system's accuracy can be represented with the mean three-dimensional displacement vector, which yielded 0.6 mm (with an overall SD of 0.9 mm) for the fusion of DRRs and X-ray images. Average deviations between known translational errors and calculations varied from - 0.3 to 0.6 mm with a standard deviation in the range of 0.6-1.2 mm. The marker matching algorithm yielded a three-dimensional uncertainty of 0.3 rum (overall SD: 0.4 mm), with averages ranging from 0.0 to 0.3 mm and a standard deviation in the range between 0.3 and 0.4 turn.Conclusions: The stereoscopic X-ray imaging device integrated with the real-time infrared tracking device represents a positioning tool allowing for the geometrical accuracy that is required for conformal radiation therapy of abdominal and pelvic lesions, within an acceptable time-frame. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.