Design trade-off between spatial resolution and power consumption in CMOS biosensor circuit based on millimeter-wave LC oscillator array
Design trade-off between spatial resolution and power consumption in CMOS biosensor circuit based on millimeter-wave LC oscillator array
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DOI：
10.7567/jjap.57.03ec02
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发表时间：
2018-01
影响因子：
1.5
通讯作者：
Maya Matsunaga;A. Kobayashi;K. Nakazato;K. Niitsu
中科院分区：
文献类型：
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作者：
Maya Matsunaga;A. Kobayashi;K. Nakazato;K. Niitsu
在本文中，我们描述了基于 LC 振荡器的 CMOS 生物传感器中空间分辨率和功耗之间的权衡，该生物传感器可以通过观察由于生物分子复介电常数变化而引起的共振频移来检测生物分子。最佳工作频率和传感器输出图像分辨率的提高需要减小电感器的尺寸。然而，虽然功耗增加，但需要增加交叉耦合晶体管的跨导才能达到振荡条件。我们使用 SPICE 仿真确认了该传感器的空间分辨率和功耗之间的权衡。使用65 nm CMOS工艺制造测试芯片，并测量峰值频率和功耗的转变。当电感外径为46μm时，功耗为31.2mW，与仿真结果吻合良好。
In this paper, we describe a trade-off between spatial resolution and power consumption in an LC oscillator-based CMOS biosensor, which can detect biomolecules by observing the resonance frequency shift due to changes in the complex permittivity of the biomolecules. The optimal operating frequency and improvement in the image resolution of the sensor output require a reduction in the size of the inductor. However, it is necessary to increase the transconductance of the cross-coupling transistor to achieve the oscillation condition, although the power consumption increases. We confirmed the trade-off between the spatial resolution and the power consumption of this sensor using SPICE simulation. A test chip was fabricated using a 65 nm CMOS process, and the transition in the peak frequency and the power consumption were measured. When the outer diameter of the inductor was 46 µm, the power consumption was 31.2 mW, which matched well with the simulation results.