OCT assessment of non-cavitated occlusal carious lesions by variation of incidence angle of probe light and refractive index matching
OCT assessment of non-cavitated occlusal carious lesions by variation of incidence angle of probe light and refractive index matching
复制标题
DOI：
10.1016/j.jdent.2017.05.005
复制
发表时间：
2017-07-01
影响因子：
4.4
通讯作者：
Schneider, Hartmut
中科院分区：
文献类型：
--
作者：
Park, Kyung-Jin;Haak, Rainer;Schneider, Hartmut
目的：评价(1)光谱域光学相干断层扫描(SD-OCT)对非空洞牙合病损的检测和评价；(2)不同探头入射角(AI)和折射率匹配(RIM)对非空洞牙合龋损的检测和评价。18个感兴趣区(ROI)在不同AI(0度、+/-5度、+/-10度、+/-15度)和0度有无应用甘油的情况下进行SD-OCT成像。以X线微计算机断层扫描(MU CT)为验证标准。根据病变范围将MU CT和OCT信号分为：1-声信号，2-病变局限于一半牙釉质，3-病变局限于牙釉质，4-病变累及牙本质。评估两种方法之间的一致性。进行了检验员内和检验员间的可重复性分析。统计学处理：Cohen‘s Kappa系数(.)、Spearman’s Rho相关系数(r(S))和Wilcoxon检验(α=0.153.0 5)。结果：在AI为0°时，Mu CT与OCT有较好的一致性(Kappa=0.0 5，P=0.0 2)。随着铝含量的变化，结果基本一致(kappa=0.607)。SPEARMAN两种方法的相关性分别为0.428，0.75与AI，0.573与甘油。检查者内和检查者间分析的Kappa值分别在0.81和0.88之间，在0.25和0.73之间。结论：AI的变异提高了非空洞咬合龋损的检测能力。RIM可以提高信噪比。
Objectives: This study evaluated (1) the detection and assessment of non-cavitated occlusal carious lesions by spectral domain optical coherence tomography (SD-OCT) and (2) the impact of varying angle of incidence (AI) of probe light and refractive index matching (RIM).Methods: Nine extracted human molars with 18 occlusal lesions (ICDAS code 2) were visually selected. 18 regions of interest (ROI) were imaged with SD-OCT under varying AI (0 degrees,+/- 5 degrees,+/- 10 degrees,+/- 15 degrees) and with/without application of glycerine at 0 degrees. X-ray micro computed tomography (mu CT) was used as a validation standard. mu CT and OCT signals were categorized according to the lesion extent: 1-sound, 2-lesion limited to half of enamel, 3-lesion limited to enamel, 4-lesion into dentin. Agreement between both methods was assessed. Intra- and inter-examiner reproducibility analyses were conducted. Statistics: Cohen's kappa coefficient (.), Spearman's rho correlation (r(s)) and Wilcoxon test (alpha= 0.05).Results: Slight to moderate agreement (kappa = 0.153) between mu CT and OCT was obtained at an AI of 0 degrees (Wilcoxon: p = 0.02). With variation of Al a substantial agreement (kappa = 0.607) was observed (p = 0.74). Spearman's correlation between both methods was 0.428 at 0 degrees, 0.75 with varying AI and 0.573 with glycerine. Kappa values for intra- and inter-examiner analysis ranged between 0.81 and 0.88 and between 0.25 and 0.73, respectively.Conclusion: Variation of AI improves the detectability of non-cavitated occlusal carious lesions. RIM can enhance signal-to-noise ratio.