Palladium-Catalyzed Intermolecular C3 Alkenylation of Indoles Using Oxygen as the Oxidant
Palladium-Catalyzed Intermolecular C3 Alkenylation of Indoles Using Oxygen as the Oxidant
复制标题
以氧气为氧化剂的钯催化吲哚分子间 C3 烯基化
DOI：
10.1021/ol302840b
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发表时间：
2012-12-07
期刊：
影响因子：
5.2
通讯作者：
Wang, Yong-Qiang
中科院分区：
文献类型：
--
作者：
Chen, Wen-Liang;Gao, Ya-Ru;Wang, Yong-Qiang
研究了一种以氧为氧化剂，钯催化的吲哚分子间C3直接烯化反应。该反应具有完全的区域选择性和立体选择性。所有产物均为c3位的e -异构体，未检测到z -异构体或2-取代产物。
A general and efficient palladium-catalyzed intermolecular direct C3 alkenylation of indoles using oxygen as the oxidant has been developed. The reaction is of complete regio- and stereoselectivity. All products are E-isomers at the C3-position, and no Z-isomers or 2-substituted product can be detected.