Diagnostic performance of body mass index to identify excess body fat in children with cerebral palsy
Diagnostic performance of body mass index to identify excess body fat in children with cerebral palsy
复制标题
体重指数对脑性瘫痪患儿体脂过多的诊断价值
DOI：
10.1111/dmcn.13714
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发表时间：
2018-07-01
影响因子：
3.8
通讯作者：
Schoenau, Eckhard
中科院分区：
文献类型：
--
作者：
Duran, Ibrahim;Schulze, Josefa;Schoenau, Eckhard
目的根据世界卫生组织（WHO）、世界肥胖联合会（WOF）、和德国肥胖症协会（DAG），以确定脑瘫儿童（CP）体内多余的脂肪方法本研究是一项单中心回顾性分析，前瞻性收集了参与一项研究的儿童和青少年CP患者的数据，康复方案。多余的身体脂肪被定义为一个身体脂肪百分比以上的第85百分位数评估双能X射线吸收measurement.ResultsIn总数，329名儿童（181名男性，148名女性）与CP有资格进行分析。平均年龄12岁4个月（标准差2岁9个月）。根据WHO、WOF和DAG的BMI超重临界值显示了以下预测我们人群中过量体脂的敏感性和特异性：WHO：敏感性0.768（95%置信区间[CI] 0.636-0.870），特异性0.894（95% CI 0.851-0.928）; WOF：灵敏度0.696（95% CI 0.559-0.812），特异性0.934（95%CI 0.898-0.960）;达格：灵敏度0.411（95% CI 0.281-0.550），特异性0.993体重指数在CP患儿中的特异性高，但敏感性低。因此，当仅使用BMI评估过量体脂时，正常体重肥胖的CP儿童被忽略了。
AimTo assess the diagnostic performance of body mass index (BMI) cut-off values according to recommendations of the World Health Organization (WHO), the World Obesity Federation (WOF), and the German Society for Adiposity (DAG) to identify excess body fat in children with cerebral palsy (CP).MethodThe present study was a monocentric retrospective analysis of prospectively collected data among children and adolescents with CP participating in a rehabilitation programme. Excess body fat was defined as a body fat percentage above the 85th centile assessed by dual-energy X-ray absorptiometry.ResultsIn total, 329 children (181 males, 148 females) with CP were eligible for analysis. The mean age was 12years 4months (standard deviation 2y 9mo). The BMI cut-off values for overweight' according to the WHO, WOF, and DAG showed the following sensitivities and specificities for the prediction of excess body fat in our population: WHO: sensitivity 0.768 (95% confidence interval [CI] 0.636-0.870), specificity 0.894 (95% CI 0.851-0.928); WOF: sensitivity 0.696 (95% CI 0.559-0.812), specificity 0.934 (95% CI 0.898-0.960); DAG: sensitivity 0.411 (95% CI 0.281-0.550), specificity 0.993 (95% CI 0.974-0.999).InterpretationBody mass index showed high specificity, but low sensitivity in children with CP. Thus, normal-weight obese' children with CP were overlooked, when assessing excess body fat only using BMI.