Moderate levels of depression predict sexual transmission risk in HIV-infected MSM: a longitudinal analysis of data from six sites involved in a "prevention for positives" study.
Moderate levels of depression predict sexual transmission risk in HIV-infected MSM: a longitudinal analysis of data from six sites involved in a "prevention for positives" study.
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DOI：
10.1007/s10461-013-0462-8
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发表时间：
2013-06
影响因子：
4.4
通讯作者：
Safren, Steven A.
中科院分区：
文献类型：
--
作者：
O'Cleirigh, Conall;Newcomb, Michael E.;Mayer, Kenneth H.;Skeer, Margie;Traeger, Lara;Safren, Steven A.
抑郁症与HIV高度并存，并可能导致感染HIV的MSM(美国最大的HIV风险群体)增加性传播风险行为(TRB)。然而，对这种影响的检查并不一致。本次对746例男男性接触者HIV感染的纵向分析来自于一项多点的“阳性预防”研究。抑郁症和TRB之间出现了一种非线性关联。中度抑郁(与低水平或高水平相比)与在12个月的随访中性行为风险行为的几率较小的下降有关。在艾滋病毒初级保健环境中评估抑郁症可能有助于识别有风险的人，将抑郁症的治疗纳入二级预防和治疗举措可能会降低性风险的可能性，并有助于控制MSM中的流行病。
Depression is highly comorbid with HIV and may contribute to increased sexual transmission risk behavior (TRB) amongst HIV-infected MSM, the largest risk group for HIV in the U.S. However, examinations of this effect are inconsistent. The present longitudinal analyses of 746 HIV-infected MSM is from a multi-site “prevention for positives” study. A non-linear association between depression and TRB emerged. Moderate levels of depression (compared to either low or high levels) were associated with a more modest decline in the odds of sexual risk behavior over 12-month follow-up. Assessing depression in HIV primary care settings may help to identify those at risk and integrating the treatment of depression in to secondary prevention and treatment initiatives may decrease the likelihood of sexual risk and help to contain the epidemic among MSM.
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影响因子：
4.4
作者：
Myers, Janet J.;Shade, Starley B.;Rose, Carol Dawson;Koester, Kimberly;Maiorana, Andre;Malitz, Faye E.;Bie, Jennifer;Kang-Dufour, Mi-Suk;Morin, Stephen F.
通讯作者：
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影响因子：
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Allgöwer, A;Wardle, J;Steptoe, A
通讯作者：
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