Severe hypophosphatemia following the institution of enteral feedings.
Severe hypophosphatemia following the institution of enteral feedings.
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肠内喂养后出现严重的低磷血症。
DOI：
10.1001/archsurg.1989.01410110087016
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发表时间：
1989
影响因子：
--
通讯作者：
P. Eisenberg
中科院分区：
文献类型：
--
作者：
Michael E. Hayek;P. Eisenberg
虽然严重的低磷血症已被确认为再喂养综合征，但它并不是肠内营养的常见并发症。本研究旨在确定与肠内途径碳水化合物给药相关的重度低磷血症（低于0.32 mmol/L [低于1.0 mg/dL]）病例。血清磷水平进行了评估时，25例患者入院时，两个中西部教学医院和他们的术后肠内支持在外科重症监护室。初始血清磷水平范围为0.77 - 1.55 mmol/L（2.4 - 4.8 mg/dL），血清钙水平范围为1.80 - 2.44 mmol/L（7.2 - 9.8 mg/dL）。从开始等渗肠内喂养后2至5天，血清磷水平降至0.16至0.39 mmol/L（0.5至1.2 mg/dL）。仅口服补充剂可在2至10天内纠正血清磷水平。高代谢需求患者的每日磷需求量可能高于常规等渗肠内配方中的磷需求量。
Although severe hypophosphatemia has been recognized in refeeding syndromes, it is not a commonly reported complication of enteral nutrition. The present study was designed to identify cases of severe hypophosphatemia (less than 0.32 mmol/L [less than 1.0 mg/dL]) related to the administration of carbohydrates via the enteral route. Serum phosphorus levels were evaluated at the time of admission of 25 patients to two midwestern teaching hospitals and during their postoperative enteral support in the surgical intensive care unit. The initial serum phosphorus levels ranged from 0.77 to 1.55 mmol/L (2.4 to 4.8 mg/dL), serum calcium levels ranged from 1.80 to 2.44 mmol/L (7.2 to 9.8 mg/dL). From two to five days following the initiation of isotonic enteral feedings, the serum phosphorus level decreased to 0.16 to 0.39 mmol/L (0.5 to 1.2 mg/dL). Serum phosphorus levels were corrected within two to ten days with oral supplementation only. Patients with high metabolic demand may have a higher daily requirement for phosphorus than that available in routine isotonic enteral formulas.