Genome of Ochrobactrum anthropi ATCC 49188T, a Versatile Opportunistic Pathogen and Symbiont of Several Eukaryotic Hosts
Genome of Ochrobactrum anthropi ATCC 49188T, a Versatile Opportunistic Pathogen and Symbiont of Several Eukaryotic Hosts
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DOI：
10.1128/jb.05335-11
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发表时间：
2011-08-01
影响因子：
3.2
通讯作者：
Tolmasky, Marcelo E.
中科院分区：
文献类型：
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作者：
Chain, Patrick S. G.;Lang, Dorothy M.;Tolmasky, Marcelo E.
人苍白杆菌是一种常见的土壤α-变形杆菌，其在广泛的生物体中定植，并且越来越被认为是一种机会性的人类病原体。可能危及生命的感染，如心内膜炎，包括在报告的O。人类感染这些报告，加上研究的数量很少，以及该生物与高致病性布鲁氏菌的系统发育接近，使得O。anthropi是细菌致病性的一个有吸引力的模型。在这里，我们报告的基因组序列的模式菌株O。人类ATCC 49188，揭示了两条染色体和四个质粒的存在。
Ochrobactrum anthropi is a common soil alphaproteobacterium that colonizes a wide spectrum of organisms and is being increasingly recognized as an opportunistic human pathogen. Potentially life-threatening infections, such as endocarditis, are included in the list of reported O. anthropi infections. These reports, together with the scant number of studies and the organism's phylogenetic proximity to the highly pathogenic brucellae, make O. anthropi an attractive model of bacterial pathogenicity. Here we report the genome sequence of the type strain O. anthropi ATCC 49188, which revealed the presence of two chromosomes and four plasmids.