Pathophysiology of Mesocestoides corti infection in the mouse
Pathophysiology of Mesocestoides corti infection in the mouse
复制标题
小鼠中绦虫感染的病理生理学
DOI：
10.1017/s0022149x00034374
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发表时间：
1982
影响因子：
1.6
通讯作者：
J. Mills
中科院分区：
文献类型：
--
作者：
T. R. White;R. Thompson;W. Penhale;D. Pass;J. Mills
摘要对两种不同初始易感性的小鼠肝脏组织学及血清酶和蛋白质的变化进行了研究。结果表明，在肝脏的侵袭和增殖过程中，ALT和AST的水平升高，而在将寄生虫包裹在肝脏和肝再生后，这两种酶的水平下降。白蛋白的进行性丢失伴随着β-和γ-球蛋白水平的增加。根据我们对这种寄生虫对宿主的影响的知识，对这些变化进行了讨论。
ABSTRACT Liver histology and serum enzyme and protein changes were studied in two strains of mice showing different initial susceptibilities to infection with Mesocestoides corti. The results show an increase in ALT and AST levels during the period of invasion and proliferation in the liver and a decrease in the levels of these two enzymes following encapsulation of the parasite in the liver and liver regeneration. A progressive loss of albumin was accompanied by increases in the levels of the beta- and gamma-globulins. These changes are discussed in the light of our knowledge of the effects of this parasite upon its host.