Mitochondrial dynamics in adaptive and maladaptive cellular stress responses.
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses.
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DOI:
10.1038/s41556-018-0133-0
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发表时间:
2018-07
影响因子:
21.3
通讯作者:
Hajnóczky G
中科院分区:
文献类型:
--
作者:
Eisner V;Picard M;Hajnóczky G
Mitochondria sense and respond to many stressors and can support either cell survival or death through energy production and signaling pathways. Mitochondrial responses depend on fusion-fission dynamics that dilute and segregate damaged mitochondria. Mitochondrial motility and inter-organellar interactions, including with the endoplasmic reticulum, also function in cellular adaptation to stress. In this Review, we discuss how stressors influence these components, and how they contribute to the complex adaptive and pathological responses that lead to disease.
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影响因子:
64.5
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Chen H;Vermulst M;Wang YE;Chomyn A;Prolla TA;McCaffery JM;Chan DC
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Green DR
DOI:
10.1083/jcb.200211046
发表时间:
2003-01-20
期刊:
The Journal of cell biology
影响因子:
--
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Chan DC