IODIXANOL - A NONIONIC ISOSMOTIC CENTRIFUGATION MEDIUM FOR THE FORMATION OF SELF-GENERATED GRADIENTS
IODIXANOL - A NONIONIC ISOSMOTIC CENTRIFUGATION MEDIUM FOR THE FORMATION OF SELF-GENERATED GRADIENTS
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DOI：
10.1006/abio.1994.1350
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发表时间：
1994-08-01
影响因子：
2.9
通讯作者：
RICKWOOD, D
中科院分区：
文献类型：
--
作者：
FORD, T;GRAHAM, J;RICKWOOD, D
本文介绍了一种新型非离子密度梯度介质碘克沙醇的物理和生物学性质。它实际上是Nycodenz的二聚体，并且与以前的碘化密度梯度介质相比，它表现出两个显著的优点-它的水溶液是等渗的，密度高达1.32 g/ml，并且它能够在1 - 3 h内形成自生梯度。它对生物材料的毒性非常低，可以在其存在下进行酶测定。(C)1994年出版社出版。
The physical and biological properties of Iodixanol, a new nonionic density gradient medium, are described in this paper. It is effectively a dimer of Nycodenz and it exhibits two significant advantages over previous iodinated density gradient media-its aqueous solutions are iso-osmotic up to a density of 1.32 g/ml and it is capable of forming self-generating gradients in 1 to 3 h. It has a very low toxicity toward biological material and enzyme assays can be carried out in its presence. (C) 1994 Academic Press, Inc.