Myalgia caused by chronic myositis associated with plasmacytosis: a case report.
Myalgia caused by chronic myositis associated with plasmacytosis: a case report.
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DOI：
10.1186/s12883-018-1123-3
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发表时间：
2018-08-14
期刊：
影响因子：
2.6
通讯作者：
Hattori N
中科院分区：
文献类型：
--
作者：
Hatano T;Takanashi M;Tsuchihashi H;Ueno SI;Hayashida A;Tsukune Y;Kanai K;Shimo Y;Hattori N
皮肤和全身浆细胞病是一种皮肤疾病，以皮肤多克隆浆细胞浸润伴多克隆高γ球蛋白血症为特征。皮肤浆细胞病的累及仅限于皮肤，主要在面部和躯干，而全身浆细胞病也累及2个或更多的器官系统。然而，尚无浆细胞增多症引起的炎症性肌炎的报道。在此，我们报告一例浆液细胞增多症患者，由于炎症性肌炎而发展为肌痛和易疲劳。54岁男性，面部、胸部和背部皮肤浆细胞病，自45岁以来有非典型面部和下肢疼痛及易疲劳病史。肌力检查显示双侧腓肠肌无力伴肌痛。血常规分析结果，包括肌酸激酶和甲状腺功能，正常，但一些炎症标志物和自身抗体水平升高。此外，下肢磁共振成像和腓肠肌活检显示炎性肌炎类似多发性肌炎。强的松龙改善了他的浆细胞增多症、肌痛和下肢无力。患者被诊断为浆液细胞增多症引起的炎症性肌炎。鉴于浆细胞增多症曾被报道破坏免疫状态，该患者的肌炎可能与异常自身免疫性炎症有关。因此，神经科医生和医生应该意识到浆细胞增多症可能与炎症性肌炎伴肌痛有关。
Cutaneous and systemic plasmacytosis are skin disorders characterized by cutaneous polyclonal plasma cell infiltration accompanied by polyclonal hypergammaglobulinemia. Cutaneous plasmacytosis involvement is limited to the skin, mainly on the face and trunk, while systemic plasmacytosis also involves 2 or more organ systems. However, there have been no reports of inflammatory myositis due to plasmacytosis. Here, we report a patient with plasmacytosis who developed myalgia and easy fatigability due to inflammatory myositis. A 54-year-old man with cutaneous plasmacytosis on the face, chest, and back complained of a history of atypical facial and lower leg pain and easy fatigability since the age of 45 years. Muscle-strength tests revealed bilateral trivial gastrocnemius weakness with myalgia. The results of routine blood analysis, including creatine kinase and thyroid function, were normal, but levels of several inflammation markers and autoantibodies were elevated. Additionally, lower leg magnetic resonance imaging and gastrocnemius muscle biopsy revealed inflammatory myositis mimicking polymyositis. His plasmacytosis, myalgia, and lower leg weakness were ameliorated by prednisolone. The patient was diagnosed with inflammatory myositis due to plasmacytosis. Given that plasmacytosis has previously been reported to disrupt the immune status, myositis in this patient might have been associated with abnormal autoimmune inflammation. Neurologists and physicians should thus be aware that plasmacytosis might be associated with inflammatory myositis accompanied by myalgia.
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DOI：
10.1016/s0190-9622(98)70131-8
发表时间：
1998-04-01
影响因子：
13.8
作者：
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通讯作者：
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影响因子：
13.8
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影响因子：
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作者：
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通讯作者：
MORI, S
影响因子：
13.8
作者：
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DOI：
10.1016/s0190-9622(97)70046-x
发表时间：
1997-05-01
影响因子：
13.8
作者：
Shimizu, S;Tanaka, M;HanYaku, H
通讯作者：
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